View source for 6vjz


==CryoEM structure of Hrd1-Usa1/Der1/Hrd3 complex of the expected topology==
<StructureSection load='6vjz' size='340' side='right'caption='[[6vjz]], [[Resolution|resolution]] 4.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6vjz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VJZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VJZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vjz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vjz OCA], [https://pdbe.org/6vjz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vjz RCSB], [https://www.ebi.ac.uk/pdbsum/6vjz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vjz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DER1_YEAST DER1_YEAST] Component of the endoplasmic reticulum-associated degradation (ERAD) pathway. Specifically required for the ERAD-L pathway which mediates the degradation of proteins with misfolded lumenal domains within the endoplasmic reticulum.<ref>PMID:16873066</ref> <ref>PMID:20005842</ref> <ref>PMID:23363603</ref> <ref>PMID:8631297</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Rapoport TA]]
[[Category: Wu X]]