View source for 8jfl


==PhK holoenzyme in active state, muscle isoform==
<StructureSection load='8jfl' size='340' side='right'caption='[[8jfl]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8jfl]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JFL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JFL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=FAR:FARNESYL'>FAR</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jfl OCA], [https://pdbe.org/8jfl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jfl RCSB], [https://www.ebi.ac.uk/pdbsum/8jfl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jfl ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/KPB1_HUMAN KPB1_HUMAN] Glycogen storage disease due to muscle phosphorylase kinase deficiency. The disease is caused by variants affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/KPB1_HUMAN KPB1_HUMAN] Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Xiao JY]]
[[Category: Yang XK]]