View source for 8tqz


==Eukaryotic translation initiation factor 2B with a mutation (L516A) in the delta subunit==
<StructureSection load='8tqz' size='340' side='right'caption='[[8tqz]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8tqz]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TQZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TQZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tqz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tqz OCA], [https://pdbe.org/8tqz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tqz RCSB], [https://www.ebi.ac.uk/pdbsum/8tqz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tqz ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/EI2BA_HUMAN EI2BA_HUMAN] Cree leukoencephalopathy;Late infantile CACH syndrome;Ovarioleukodystrophy. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/EI2BA_HUMAN EI2BA_HUMAN] Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Anand A]]
[[Category: Deal A]]
[[Category: Lawrence R]]
[[Category: Marqusee S]]
[[Category: Sangwan S]]
[[Category: Shoemaker S]]
[[Category: Wang L]]
[[Category: Watler P]]