View source for 9cbe


==Structure of a type III antifreeze protein isoform HPLC12 re-refined using standard protocols==
<StructureSection load='9cbe' size='340' side='right'caption='[[9cbe]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9cbe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zoarces_americanus Zoarces americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9CBE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9CBE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9cbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9cbe OCA], [https://pdbe.org/9cbe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9cbe RCSB], [https://www.ebi.ac.uk/pdbsum/9cbe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9cbe ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ANP12_ZOAAM ANP12_ZOAAM] Contributes to protect fish blood from freezing at subzero sea water temperatures. Lowers the blood freezing point. Binds to nascent ice crystals and prevents further growth.
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== Publication Abstract from PubMed ==
The manuscript ;Modeling a unit cell: crystallographic refinement procedure using the biomolecular MD simulation platform Amber' presents a novel protein structure refinement method claimed to offer improvements over traditional techniques like Refmac5 and Phenix. Our re-evaluation suggests that while the new method provides improvements, traditional methods achieve comparable results with less computational effort.

In some cases more complicated approaches to refinement of macromolecular structures are not necessary.,Dauter Z, Wlodawer A IUCrJ. 2024 Jul 1;11(Pt 4):643-644. doi: 10.1107/S2052252524005803. PMID:38958017<ref>PMID:38958017</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Zoarces americanus]]
[[Category: Dauter Z]]
[[Category: Wlodawer A]]