View source for 9ivc


==Cryo-EM structure of AbA-bound Aur1-Kei1 complex==
<StructureSection load='9ivc' size='340' side='right'caption='[[9ivc]], [[Resolution|resolution]] 3.17&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9ivc]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Aureobasidium_pullulans Aureobasidium pullulans] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IVC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9IVC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.17&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1L3I:(2~{S})-3-methyl-2-(methylamino)-3-oxidanyl-butanoic+acid'>A1L3I</scene>, <scene name='pdbligand=A1L3J:(2~{R},3~{R})-3-methyl-2-oxidanyl-pentanoic+acid'>A1L3J</scene>, <scene name='pdbligand=IIL:ISO-ISOLEUCINE'>IIL</scene>, <scene name='pdbligand=MEA:N-METHYLPHENYLALANINE'>MEA</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ivc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ivc OCA], [https://pdbe.org/9ivc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ivc RCSB], [https://www.ebi.ac.uk/pdbsum/9ivc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ivc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AUR1_YEAST AUR1_YEAST] Catalytic component of the inositol phosphorylceramide synthase which catalyzes the addition of a phosphorylinositol group onto ceramide to form inositol phosphorylceramide, an essential step in sphingolipid biosynthesis.<ref>PMID:10888667</ref> <ref>PMID:19047657</ref> <ref>PMID:19726565</ref> <ref>PMID:9092515</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Aureobasidium pullulans]]
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Gong X]]
[[Category: Wu X]]
[[Category: Xie T]]