View source for 9mzh


==Cryo-EM structure of the Nipah virus polymerase containing the connecting domain==
<StructureSection load='9mzh' size='340' side='right'caption='[[9mzh]], [[Resolution|resolution]] 2.99&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9mzh]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Henipavirus_nipahense Henipavirus nipahense]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9MZH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9MZH FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.99&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9mzh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9mzh OCA], [https://pdbe.org/9mzh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9mzh RCSB], [https://www.ebi.ac.uk/pdbsum/9mzh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9mzh ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PHOSP_NIPAV PHOSP_NIPAV] Essential component of the RNA polymerase transcription and replication complex. Binds the viral ribonucleocapsid and positions the L polymerase on the template (By similarity). May play a role to prevent the establishment of cellular antiviral state by binding to host STAT1 in the cytoplasm. This activity is not as strong as that of V and W.
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</StructureSection>
[[Category: Henipavirus nipahense]]
[[Category: Large Structures]]
[[Category: Chen ZH]]
[[Category: Liang B]]