View source for 9oeg


==Structure of the human astrovirus VA1 capsid spike bound to antibody 2A2==
<StructureSection load='9oeg' size='340' side='right'caption='[[9oeg]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9oeg]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Astrovirus_VA1 Astrovirus VA1] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9OEG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9OEG FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.05&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9oeg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9oeg OCA], [https://pdbe.org/9oeg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9oeg RCSB], [https://www.ebi.ac.uk/pdbsum/9oeg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9oeg ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CAPSD_HASVA CAPSD_HASVA] The capsid polyprotein VP90 self-assembles and undergoes a proteolytic cleavage by host caspases to yield the immature VP70 virion.[UniProtKB:Q9IFX1]  Self-assembles to form an icosahedral capsid with a T=3 symmetry, about 43 nm in diameter.[UniProtKB:O12792]  Forms the spikes at the surface of the virion (PubMed:38416796). Plays a role in the attachment to target host cell (By similarity).[UniProtKB:O12792]<ref>PMID:38416796</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Astrovirus VA1]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Balasco Serrao VH]]
[[Category: DuBois RM]]
[[Category: Dzimianski JV]]
[[Category: Ghosh A]]