View source for 9t3x


==cryo-EM strucutre of CPSF160-WDR33-ZC3H18==
<StructureSection load='9t3x' size='340' side='right'caption='[[9t3x]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9t3x]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9T3X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9T3X FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9t3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9t3x OCA], [https://pdbe.org/9t3x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9t3x RCSB], [https://www.ebi.ac.uk/pdbsum/9t3x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9t3x ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CPSF1_HUMAN CPSF1_HUMAN] Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.<ref>PMID:14749727</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Chand MK]]
[[Category: Conti E]]
[[Category: Garland W]]
[[Category: Jensen TH]]
[[Category: Keidel A]]
[[Category: Kuhn CC]]
[[Category: Todesca S]]
[[Category: Williams K]]