View source for Blue copper oxidase CueO

<StructureSection load='2fqf' size='350' side='right' caption='Structure of E. coli blue copper oxidase CueO complex with two Cu+2 ions (orange), Cu-O-Cu and citrate (PDB code [[2fqf]]).' scene='59/593960/Cv/1'>

== Function ==

'''Blue copper oxidase CueO''' (CueO) or '''laccase CueO''' is an ''E. coli'' enzyme which catalyzes the conversion of Cu+1 to Cu+2 resulting in the detoxification of copper by the prevention of its uptake into the cytoplasm.<ref>PMID:11527384</ref> 

== Relevance ==

CueO is involved in prevention of oxidative damage in the periplasm.

== Structural highlights ==

The Cu moieties (Cu-O-Cu and Cu+2) are coordinated by at least 2 histidine residues: <scene name='59/593960/Cv/7'>Cu and Cu-O-Cu</scene> and <scene name='59/593960/Cv/8'>single Cu</scene>.<ref>PMID:17217912</ref>

==3D structures of blue copper oxidase CueO==
[[Blue copper oxidase CueO 3D structures]]

</StructureSection>


== References ==
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