View source for Phosphate-binding protein

<StructureSection load='' size='350' side='right' scene='48/488458/Cv/1' caption='E. coli phosphate-binding protein complex with phosphate [[1pbp]]'>
== Function ==
'''Phosphate-binding protein''' (PBP) binds phosphate (Pi) with high affinity.  PBP is involved in various biological processes like cell cycle regulation.  PBP is produced under conditions of low Pi concentration.  It binds Pi in the periplasm and transfers it to a membrane protein which transports it to the cytoplasm.  PBP undergoes conformational change upon binding to Pi<ref>PMID:25338617</ref>.

== Structural highlights ==
The <scene name='48/488458/Cv/4'>PBP phosphate-binding site</scene> is highly selective.  It can bind monobasic and dibasic phosphate but does not bind sulfate<ref>PMID:7929197</ref>.
</StructureSection>
==3D structures of phosphate-binding protein==
[[phosphate-binding protein 3D structures]]

== References ==
<references/>
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