6alk: Difference between revisions

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~~'''Unreleased structure'''~~

The ~~entry 6alk~~ is ~~ON HOLD~~

==NMR solution structure of the major beech pollen allergen Fag s 1==

== Structural highlights ==

<table><tr><td colspan='2'>[[6alk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Fagus_sylvatica Fagus sylvatica]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ALK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ALK FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6alk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6alk OCA], [https://pdbe.org/6alk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6alk RCSB], [https://www.ebi.ac.uk/pdbsum/6alk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6alk ProSAT]</span></td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/B7TWE6_FAGSY B7TWE6_FAGSY]

== Publication Abstract from PubMed ==

Fag s 1 is a member of the Pathogen Related protein family 10 (PR-10) and can elicit cross-reaction with IgE antibodies produced against the birch pollen allergen Bet v 1. The Nuclear Magnetic Resonance (NMR) structure of Fag s 1 is presented along with its dynamic properties. It shares 66% identity with Bet v 1 and exhibits the expected three alpha-helices and seven beta-sheets arranged as a semi-beta barrel and exposing the residues mapped as the Bet v 1 IgE epitope. The structural dynamics of Fag s 1 were monitored on the fast and intermediate timescales, using relaxation rates. The complex dynamics of Fag s 1 are closely related to the internal cavity, and they modulate IgE and ligand binding.

~~Authors:~~ Moraes~~, A.H.~~, Asam~~, A.~~, Almeida~~, F.C.L.~~, Wallner, M., Ferreira, F., Valente~~, A~~.P.

Structural basis for cross-reactivity and conformation fluctuation of the major beech pollen allergen Fag s 1.,Moraes AH, Asam C, Almeida FCL, Wallner M, Ferreira F, Valente AP Sci Rep. 2018 Jul 12;8(1):10512. doi: 10.1038/s41598-018-28358-1. PMID:30002383<ref>PMID:30002383</ref>

~~Description: NMR solution structure~~ of the ~~major beech pollen allergen Fag s 1~~

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>

[[Category: ~~Unreleased Structures~~]]

</div>

[[Category: ~~Moraes, A.H~~]]

[[Category: Almeida~~, F.C.L~~]]

== References ==

[[Category: Asam, A]]

[[Category: ~~Valente, A.P~~]]

__TOC__

[[Category: ~~Wallner, M~~]]

</StructureSection>

[[Category: ~~Ferreira, F~~]]

[[Category: Fagus sylvatica]]

[[Category: Large Structures]]

[[Category: Almeida FCL]]

[[Category: Asam A]]

[[Category: Ferreira F]]

[[Category: Moraes AH]]

[[Category: Valente AP]]

[[Category: Wallner M]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6alk is ON HOLD
+==NMR solution structure of the major beech pollen allergen Fag s 1==
+<StructureSection load='6alk' size='340' side='right'caption='[[6alk]]' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6alk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Fagus_sylvatica Fagus sylvatica]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ALK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ALK FirstGlance]. <br>
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6alk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6alk OCA], [https://pdbe.org/6alk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6alk RCSB], [https://www.ebi.ac.uk/pdbsum/6alk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6alk ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/B7TWE6_FAGSY B7TWE6_FAGSY]
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Fag s 1 is a member of the Pathogen Related protein family 10 (PR-10) and can elicit cross-reaction with IgE antibodies produced against the birch pollen allergen Bet v 1. The Nuclear Magnetic Resonance (NMR) structure of Fag s 1 is presented along with its dynamic properties. It shares 66% identity with Bet v 1 and exhibits the expected three alpha-helices and seven beta-sheets arranged as a semi-beta barrel and exposing the residues mapped as the Bet v 1 IgE epitope. The structural dynamics of Fag s 1 were monitored on the fast and intermediate timescales, using relaxation rates. The complex dynamics of Fag s 1 are closely related to the internal cavity, and they modulate IgE and ligand binding.
-Authors: Moraes, A.H., Asam, A., Almeida, F.C.L., Wallner, M., Ferreira, F., Valente, A.P.
+Structural basis for cross-reactivity and conformation fluctuation of the major beech pollen allergen Fag s 1.,Moraes AH, Asam C, Almeida FCL, Wallner M, Ferreira F, Valente AP Sci Rep. 2018 Jul 12;8(1):10512. doi: 10.1038/s41598-018-28358-1. PMID:30002383<ref>PMID:30002383</ref>
-Description: NMR solution structure of the major beech pollen allergen Fag s 1
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-[[Category: Unreleased Structures]]
+</div>
-[[Category: Moraes, A.H]]
+<div class="pdbe-citations 6alk" style="background-color:#fffaf0;"></div>
-[[Category: Almeida, F.C.L]]
+== References ==
-[[Category: Asam, A]]
+<references/>
-[[Category: Valente, A.P]]
+__TOC__
-[[Category: Wallner, M]]
+</StructureSection>
-[[Category: Ferreira, F]]
+[[Category: Fagus sylvatica]]
+[[Category: Large Structures]]
+[[Category: Almeida FCL]]
+[[Category: Asam A]]
+[[Category: Ferreira F]]
+[[Category: Moraes AH]]
+[[Category: Valente AP]]
+[[Category: Wallner M]]