4u82: Difference between revisions

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<StructureSection load='4u82' size='340' side='right'caption='[[4u82]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
<StructureSection load='4u82' size='340' side='right'caption='[[4u82]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4u82]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staan Staan]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U82 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U82 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4u82]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_N315 Staphylococcus aureus subsp. aureus N315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U82 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4U82 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FPS:S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL]+TRIHYDROGEN+THIODIPHOSPHATE'>FPS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.66&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">uppS, SA1103 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158879 STAAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FPS:S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL]+TRIHYDROGEN+THIODIPHOSPHATE'>FPS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u82 OCA], [http://pdbe.org/4u82 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4u82 RCSB], [http://www.ebi.ac.uk/pdbsum/4u82 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4u82 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4u82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u82 OCA], [https://pdbe.org/4u82 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4u82 RCSB], [https://www.ebi.ac.uk/pdbsum/4u82 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4u82 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ISPT_STAAN ISPT_STAAN]] Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.[HAMAP-Rule:MF_01139]  
[https://www.uniprot.org/uniprot/ISPT_STAAN ISPT_STAAN] Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.[HAMAP-Rule:MF_01139]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Staan]]
[[Category: Staphylococcus aureus subsp. aureus N315]]
[[Category: Oldfield, E]]
[[Category: Oldfield E]]
[[Category: Zhu, W]]
[[Category: Zhu W]]
[[Category: Alkyl and aryl transferase]]
[[Category: Anti-bacterial agent]]
[[Category: Benzoate]]
[[Category: Biosynthetic pathway]]
[[Category: Cell wall]]
[[Category: Diphosphonate]]
[[Category: Drug discovery]]
[[Category: High-throughput screening assay]]
[[Category: Methicillin]]
[[Category: Microbial sensitivity test]]
[[Category: Pyrrolidinone]]
[[Category: Staphylococcus aureus]]
[[Category: Terpene]]
[[Category: Transferase]]

Latest revision as of 07:25, 27 September 2023

Structure of S. aureus undecaprenyl diphosphate synthase in complex with FSPP and sulfate

4u82, resolution 1.66Å

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