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==Crystal structure of Helicobacter pylori Undecaprenyl Pyrophosphate Synthase==
==Crystal structure of Helicobacter pylori Undecaprenyl Pyrophosphate Synthase==
<StructureSection load='2d2r' size='340' side='right' caption='[[2d2r]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
<StructureSection load='2d2r' size='340' side='right'caption='[[2d2r]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2d2r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D2R FirstGlance]. <br>
<table><tr><td colspan='2'>[[2d2r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D2R FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Di-trans,poly-cis-decaprenylcistransferase Di-trans,poly-cis-decaprenylcistransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.31 2.5.1.31] </span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88&#8491;</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d2r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d2r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2d2r RCSB], [http://www.ebi.ac.uk/pdbsum/2d2r PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d2r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d2r OCA], [https://pdbe.org/2d2r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d2r RCSB], [https://www.ebi.ac.uk/pdbsum/2d2r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d2r ProSAT]</span></td></tr>
<table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ISPT_HELPY ISPT_HELPY] Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d2/2d2r_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d2/2d2r_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d2r ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2d2r" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Di-trans,poly-cis-decaprenylcistransferase]]
[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
[[Category: Chen, C L.]]
[[Category: Large Structures]]
[[Category: Cheng, Y L.]]
[[Category: Chen CL]]
[[Category: Cheng, Y S.]]
[[Category: Cheng YL]]
[[Category: Guo, R T.]]
[[Category: Cheng YS]]
[[Category: Ko, T P.]]
[[Category: Guo RT]]
[[Category: Kuo, C J.]]
[[Category: Ko TP]]
[[Category: Liang, P H.]]
[[Category: Kuo CJ]]
[[Category: Wang, A H.J.]]
[[Category: Liang PH]]
[[Category: Prenyl]]
[[Category: Wang AH-J]]
[[Category: Prenyltransferase]]
[[Category: Transferase]]
[[Category: Undecaprenyl]]

Latest revision as of 08:23, 25 October 2023

Crystal structure of Helicobacter pylori Undecaprenyl Pyrophosphate Synthase

2d2r, resolution 1.88Å

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