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==Crystal structure of the isomaltulose synthase SmuA from Protaminobacter rubrum in complex with the inhibitor deoxynojirimycin==
==Crystal structure of the isomaltulose synthase SmuA from Protaminobacter rubrum in complex with the inhibitor deoxynojirimycin==
<StructureSection load='3gbe' size='340' side='right' caption='[[3gbe]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='3gbe' size='340' side='right'caption='[[3gbe]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3gbe]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GBE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GBE FirstGlance]. <br>
<table><tr><td colspan='2'>[[3gbe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Serratia_plymuthica Serratia plymuthica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GBE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GBE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NOJ:1-DEOXYNOJIRIMYCIN'>NOJ</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3gbd|3gbd]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NOJ:1-DEOXYNOJIRIMYCIN'>NOJ</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Isomaltulose_synthase Isomaltulose synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.11 5.4.99.11] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gbe OCA], [https://pdbe.org/3gbe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gbe RCSB], [https://www.ebi.ac.uk/pdbsum/3gbe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gbe ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gbe OCA], [http://pdbe.org/3gbe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gbe RCSB], [http://www.ebi.ac.uk/pdbsum/3gbe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3gbe ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/D0VX20_SERPL D0VX20_SERPL]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 3gbe" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3gbe" style="background-color:#fffaf0;"></div>
==See Also==
*[[Trehalulose synthase|Trehalulose synthase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Isomaltulose synthase]]
[[Category: Large Structures]]
[[Category: Aghajari, N]]
[[Category: Serratia plymuthica]]
[[Category: Haser, R]]
[[Category: Aghajari N]]
[[Category: Ravaud, S]]
[[Category: Haser R]]
[[Category: Robert, X]]
[[Category: Ravaud S]]
[[Category: Deoxynojirimycin complex]]
[[Category: Robert X]]
[[Category: Glycoside hydrolase]]
[[Category: Isomerase]]
[[Category: Protaminobacter rubrum]]
[[Category: Sucrose isomerase]]

Latest revision as of 15:38, 1 November 2023

Crystal structure of the isomaltulose synthase SmuA from Protaminobacter rubrum in complex with the inhibitor deoxynojirimycin

3gbe, resolution 1.70Å

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