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==Crystal structure of the MUTB R284C mutant from crystals soaked with the inhibitor deoxynojirimycin==
==Crystal structure of the MUTB R284C mutant from crystals soaked with the inhibitor deoxynojirimycin==
<StructureSection load='4gin' size='340' side='right' caption='[[4gin]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='4gin' size='340' side='right'caption='[[4gin]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4gin]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhizobium_sp._mx-45 Rhizobium sp. mx-45]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GIN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GIN FirstGlance]. <br>
<table><tr><td colspan='2'>[[4gin]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhizobium_sp._MX-45 Rhizobium sp. MX-45]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GIN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GIN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zja|1zja]], [[2pwh|2pwh]], [[2pwe|2pwe]], [[2pwf|2pwf]], [[2pwd|2pwd]], [[2pwg|2pwg]], [[4gi6|4gi6]], [[4gi8|4gi8]], [[4gi9|4gi9]], [[4gia|4gia]], [[1zjb|1zjb]], [[4h2c|4h2c]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mutB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1071045 Rhizobium sp. MX-45])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gin OCA], [https://pdbe.org/4gin PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gin RCSB], [https://www.ebi.ac.uk/pdbsum/4gin PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gin ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Isomerase Isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.11.99 5.4.11.99] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gin OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gin RCSB], [http://www.ebi.ac.uk/pdbsum/4gin PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/M1E1F6_9HYPH M1E1F6_9HYPH]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4gin" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Isomerase]]
[[Category: Large Structures]]
[[Category: Rhizobium sp. mx-45]]
[[Category: Rhizobium sp. MX-45]]
[[Category: Aghajari, N]]
[[Category: Aghajari N]]
[[Category: Haser, R]]
[[Category: Haser R]]
[[Category: Lipski, A]]
[[Category: Lipski A]]
[[Category: Ravaud, S]]
[[Category: Ravaud S]]
[[Category: Robert, X]]
[[Category: Robert X]]
[[Category: Calcium binding]]
[[Category: Glycoside hydrolase]]
[[Category: Mutant enzyme]]
[[Category: Sucrose isomerase]]
[[Category: Trehalulose synthase]]

Latest revision as of 13:59, 8 November 2023

Crystal structure of the MUTB R284C mutant from crystals soaked with the inhibitor deoxynojirimycin

4gin, resolution 1.90Å

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