5y06: Difference between revisions

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New page: '''Unreleased structure''' The entry 5y06 is ON HOLD until Paper Publication Authors: Kumar, A., Karthikeyan, S. Description: Structural characterization of msmeg_4306 from Mycobacteri...
 
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'''Unreleased structure'''


The entry 5y06 is ON HOLD  until Paper Publication
==Structural characterization of msmeg_4306 from Mycobacterium smegmatis==
<StructureSection load='5y06' size='340' side='right'caption='[[5y06]], [[Resolution|resolution]] 2.61&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5y06]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis_MC2_155 Mycolicibacterium smegmatis MC2 155]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Y06 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.606&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5y06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y06 OCA], [https://pdbe.org/5y06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5y06 RCSB], [https://www.ebi.ac.uk/pdbsum/5y06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5y06 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0R095_MYCS2 A0R095_MYCS2]
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The MSMEG_4306 gene from Mycobacterium smegmatis encodes a protein of unknown function with 242 amino-acid residues that contains a conserved zinc-ribbon domain at its C-terminus. Here, the crystal structure of MSMEG_4306 determined by the single-wavelength anomalous dispersion method using just one zinc ion co-purified with the protein is reported. The crystal structure of MSMEG_4306 shows a coiled-coil helix domain in the N-terminal region and a zinc-ribbon domain in the C-terminal region. A structural similarity search against the Protein Data Bank using MSMEG_4306 as a query revealed two similar structures, namely CT398 from Chlamydia trachomatis and HP0958 from Helicobacter pylori, although they share only approximately 15% sequence identity with MSMEG_4306. Based on comparative analysis, it is predicted that MSMEG_4306 may be involved in secretion systems, possibly by interacting with multiple proteins or nucleic acids.


Authors: Kumar, A., Karthikeyan, S.
Crystal structure of the MSMEG_4306 gene product from Mycobacterium smegmatis.,Kumar A, Karthikeyan S Acta Crystallogr F Struct Biol Commun. 2018 Mar 1;74(Pt 3):166-173. doi:, 10.1107/S2053230X18002236. Epub 2018 Feb 26. PMID:29497021<ref>PMID:29497021</ref>


Description: Structural characterization of msmeg_4306 from Mycobacterium smegmatis
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
[[Category: Unreleased Structures]]
</div>
[[Category: Karthikeyan, S]]
<div class="pdbe-citations 5y06" style="background-color:#fffaf0;"></div>
[[Category: Kumar, A]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycolicibacterium smegmatis MC2 155]]
[[Category: Karthikeyan S]]
[[Category: Kumar A]]
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