2w1b: Difference between revisions
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<StructureSection load='2w1b' size='340' side='right' caption='[[2w1b]], [[Resolution|resolution]] 3.85Å' scene=''> | ==The structure of the efflux pump AcrB in complex with bile acid== | ||
<StructureSection load='2w1b' size='340' side='right'caption='[[2w1b]], [[Resolution|resolution]] 3.85Å' scene=''> | |||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2w1b]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2w1b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W1B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W1B FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.85Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DXC:(3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC+ACID'>DXC</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w1b OCA], [https://pdbe.org/2w1b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w1b RCSB], [https://www.ebi.ac.uk/pdbsum/2w1b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w1b ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 2w1b" style="background-color:#fffaf0;"></div> | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli | [[Category: Escherichia coli K-12]] | ||
[[Category: Large Structures]] | |||
[[Category: | [[Category: Beis K]] | ||
[[Category: | [[Category: De Gier JW]] | ||
[[Category: Gier | [[Category: Drew D]] | ||
[[Category: | [[Category: Flaig R]] | ||
[[Category: | [[Category: Iwata S]] | ||
[[Category: | [[Category: Klepsch MM]] | ||
[[Category: | [[Category: Newstead S]] | ||
[[Category: | |||
Latest revision as of 15:40, 13 December 2023
The structure of the efflux pump AcrB in complex with bile acid
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