3o63: Difference between revisions
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==Crystal Structure of Thiamin Phosphate Synthase from Mycobacterium tuberculosis== | |||
<StructureSection load='3o63' size='340' side='right'caption='[[3o63]], [[Resolution|resolution]] 2.35Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3o63]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O63 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O63 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o63 OCA], [https://pdbe.org/3o63 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o63 RCSB], [https://www.ebi.ac.uk/pdbsum/3o63 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o63 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/THIE_MYCTU THIE_MYCTU] Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<ref>PMID:21818324</ref> | |||
=== | ==See Also== | ||
*[[Thiamin phosphate synthase|Thiamin phosphate synthase]] | |||
== References == | |||
<references/> | |||
[[ | __TOC__ | ||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Begley TP]] | |||
[[Category: Begley | [[Category: Ealick SE]] | ||
[[Category: Ealick | [[Category: Guida WC]] | ||
[[Category: Guida | [[Category: Ishida K]] | ||
[[Category: Ishida | [[Category: McCulloch KM]] | ||
[[Category: McCulloch | [[Category: Ramamoorthy D]] | ||
[[Category: Ramamoorthy | |||
Latest revision as of 10:03, 14 February 2024
Crystal Structure of Thiamin Phosphate Synthase from Mycobacterium tuberculosis
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