2ouc: Difference between revisions

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{{Seed}}
[[Image:2ouc.png|left|200px]]


<!--
==Crystal structure of the MAP kinase binding domain of MKP5==
The line below this paragraph, containing "STRUCTURE_2ouc", creates the "Structure Box" on the page.
<StructureSection load='2ouc' size='340' side='right'caption='[[2ouc]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2ouc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OUC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OUC FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ouc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ouc OCA], [https://pdbe.org/2ouc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ouc RCSB], [https://www.ebi.ac.uk/pdbsum/2ouc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ouc ProSAT]</span></td></tr>
{{STRUCTURE_2ouc| PDB=2ouc |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/DUS10_HUMAN DUS10_HUMAN] Protein phosphatase involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily.<ref>PMID:22375048</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ou/2ouc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ouc ConSurf].
<div style="clear:both"></div>


===Crystal structure of the MAP kinase binding domain of MKP5===
==See Also==
 
*[[MAP kinase phosphatase|MAP kinase phosphatase]]
 
== References ==
<!--
<references/>
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__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 17400920 is the PubMed ID number.
</StructureSection>
-->
{{ABSTRACT_PUBMED_17400920}}
 
==About this Structure==
2OUC is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OUC OCA].
 
==Reference==
<ref group="xtra">PMID:17400920</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Tao, X.]]
[[Category: Large Structures]]
[[Category: Tong, L.]]
[[Category: Tao X]]
[[Category: Hydrolase]]
[[Category: Tong L]]
[[Category: Rhodanese fold]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 19:06:50 2009''

Latest revision as of 09:06, 21 February 2024

Crystal structure of the MAP kinase binding domain of MKP5

2ouc, resolution 2.20Å

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