4omh: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| (7 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Crystal structure of | |||
<StructureSection load='4omh' size='340' side='right' caption='[[4omh]], [[Resolution|resolution]] 1.64Å' scene=''> | ==Crystal structure of the bacterial diterpene cyclase COTB2 variant F149L== | ||
<StructureSection load='4omh' size='340' side='right'caption='[[4omh]], [[Resolution|resolution]] 1.64Å' scene=''> | |||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4omh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OMH OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[4omh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_melanosporofaciens Streptomyces melanosporofaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OMH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OMH FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CXS:3-CYCLOHEXYL-1-PROPYLSULFONIC+ACID'>CXS</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CXS:3-CYCLOHEXYL-1-PROPYLSULFONIC+ACID'>CXS</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4omh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4omh OCA], [https://pdbe.org/4omh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4omh RCSB], [https://www.ebi.ac.uk/pdbsum/4omh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4omh ProSAT]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/COTB2_STRMJ COTB2_STRMJ] Catalyzes the cyclization of the linear isoprenoid intermediate geranylgeranyl diphosphate to tricycclic cyclooctat-9-en-7-ol in the cyclooctatin biosynthesis pathway. Cyclooctatin is a potent inhibitor of lysophospholipase.<ref>PMID:19635410</ref> <ref>PMID:24914964</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Streptomyces melanosporofaciens]] | ||
[[Category: | [[Category: Brueck T]] | ||
[[Category: | [[Category: Goerner C]] | ||
[[Category: | [[Category: Hirte M]] | ||
[[Category: | [[Category: Janke R]] | ||
[[Category: | [[Category: Loll B]] | ||
Latest revision as of 12:40, 1 March 2024
Crystal structure of the bacterial diterpene cyclase COTB2 variant F149L
| ||||||||||||
