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==Crystal Structure of Untagged C54A Mutant Flavin Reductase (DszD) in Complex with FMN From Mycobacterium goodii==
==Crystal Structure of Untagged C54A Mutant Flavin Reductase (DszD) in Complex with FMN From Mycobacterium goodii==
<StructureSection load='3pft' size='340' side='right' caption='[[3pft]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='3pft' size='340' side='right'caption='[[3pft]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3pft]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_700504 Atcc 700504]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PFT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PFT FirstGlance]. <br>
<table><tr><td colspan='2'>[[3pft]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_goodii Mycobacterium goodii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PFT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PFT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.601&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dszD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=134601 ATCC 700504])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Oxidoreductase Oxidoreductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.38, 1.5.1.39 and 1.5.1.41 1.5.1.38, 1.5.1.39 and 1.5.1.41] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pft OCA], [https://pdbe.org/3pft PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pft RCSB], [https://www.ebi.ac.uk/pdbsum/3pft PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pft ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pft OCA], [http://pdbe.org/3pft PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3pft RCSB], [http://www.ebi.ac.uk/pdbsum/3pft PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3pft ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DSZD_MYCGD DSZD_MYCGD] An NADH:FMN oxidoreductase which supplies reduced FMN for the '4S' desulfurization pathway that removes covalently bound sulfur from dibenzothiophene (DBT) without breaking carbon-carbon bonds. Can also use FAD. Provides DszC and probably also DszA (DBT-monooxygenase and DBTO2-monooxygenase respectively) with reduced flavin (FMN and/or FAD).<ref>PMID:19144512</ref>
==See Also==
*[[Flavin reductase|Flavin reductase]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 700504]]
[[Category: Large Structures]]
[[Category: Oxidoreductase]]
[[Category: Mycobacterium goodii]]
[[Category: Gu, L]]
[[Category: Gu L]]
[[Category: Li, B]]
[[Category: Li B]]
[[Category: Li, N]]
[[Category: Li N]]
[[Category: Li, Q]]
[[Category: Li Q]]
[[Category: Liu, S]]
[[Category: Liu S]]
[[Category: Liu, X]]
[[Category: Liu X]]
[[Category: Ma, C]]
[[Category: Ma C]]
[[Category: Su, J]]
[[Category: Su J]]
[[Category: Xu, P]]
[[Category: Xu P]]
[[Category: Zhang, C]]
[[Category: Zhang C]]
[[Category: Desulfurization]]
[[Category: Flavin reductase]]

Latest revision as of 13:31, 1 March 2024

Crystal Structure of Untagged C54A Mutant Flavin Reductase (DszD) in Complex with FMN From Mycobacterium goodii

3pft, resolution 1.60Å

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