3rab: Difference between revisions

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{{Seed}}
[[Image:3rab.png|left|200px]]


<!--
==GPPNHP-BOUND RAB3A AT 2.0 A RESOLUTION==
The line below this paragraph, containing "STRUCTURE_3rab", creates the "Structure Box" on the page.
<StructureSection load='3rab' size='340' side='right'caption='[[3rab]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3rab]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RAB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RAB FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_3rab| PDB=3rab |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rab OCA], [https://pdbe.org/3rab PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rab RCSB], [https://www.ebi.ac.uk/pdbsum/3rab PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rab ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RAB3A_RAT RAB3A_RAT] Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ra/3rab_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3rab ConSurf].
<div style="clear:both"></div>


===GPPNHP-BOUND RAB3A AT 2.0 A RESOLUTION===
==See Also==
 
*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_10196122}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 10196122 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_10196122}}
 
==About this Structure==
3RAB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RAB OCA].
 
==Reference==
Structural basis of activation and GTP hydrolysis in Rab proteins., Dumas JJ, Zhu Z, Connolly JL, Lambright DG, Structure. 1999 Apr 15;7(4):413-23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10196122 10196122]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Single protein]]
[[Category: Connolly JL]]
[[Category: Connolly, J L.]]
[[Category: Dumas JJ]]
[[Category: Dumas, J J.]]
[[Category: Lambright DG]]
[[Category: Lambright, D G.]]
[[Category: Zhu Z]]
[[Category: Zhu, Z.]]
[[Category: G protein]]
[[Category: Gtp hydrolysis]]
[[Category: Hydrolase]]
[[Category: Neurotransmitter release]]
[[Category: Rab protein]]
[[Category: Vesicular trafficking]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul  3 13:04:39 2008''

Latest revision as of 12:16, 14 March 2024

GPPNHP-BOUND RAB3A AT 2.0 A RESOLUTION

3rab, resolution 2.00Å

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