4e08: Difference between revisions

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[[Image:4e08.jpg|left|200px]]


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==Crystal structure of Drosophila melanogaster DJ-1beta==
The line below this paragraph, containing "STRUCTURE_4e08", creates the "Structure Box" on the page.
<StructureSection load='4e08' size='340' side='right'caption='[[4e08]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[4e08]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E08 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E08 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_4e08|  PDB=4e08  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e08 OCA], [https://pdbe.org/4e08 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e08 RCSB], [https://www.ebi.ac.uk/pdbsum/4e08 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e08 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DJ1B_DROME DJ1B_DROME] Plays an important role in cell protection against oxidative stress and cell death by acting as a oxidative stress sensor (PubMed:16139214, PubMed:16203113, PubMed:16894167, PubMed:20457924). Does not play a role in methylglyoxal detoxification (PubMed:27903648). Plays a role in mitochondrial function together with Pink1 (PubMed:20457924). In motor neurons regulates structural synaptic plasticity of locomotor behavior as part of the PTEN-phosphatidylinositol 3-kinase pathway in response to oxygen species (ROS) levels (PubMed:30540251).<ref>PMID:16139214</ref> <ref>PMID:16203113</ref> <ref>PMID:16894167</ref> <ref>PMID:20457924</ref> <ref>PMID:27903648</ref> <ref>PMID:30540251</ref>  


===Crystal structure of Drosophila melanogaster DJ-1beta===
==See Also==
 
*[[Protein DJ-1|Protein DJ-1]]
 
== References ==
==About this Structure==
<references/>
[[4e08]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E08 OCA].
__TOC__
</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Lin, J.]]
[[Category: Large Structures]]
[[Category: Prahlad, J.]]
[[Category: Lin J]]
[[Category: Wilson, M A.]]
[[Category: Prahlad J]]
[[Category: Flavodoxin-like fold]]
[[Category: Wilson MA]]
[[Category: Motor protein]]
[[Category: Stress response]]

Latest revision as of 14:48, 14 March 2024

Crystal structure of Drosophila melanogaster DJ-1beta

4e08, resolution 2.00Å

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