2krc: Difference between revisions
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< | ==Solution structure of the N-terminal domain of Bacillus subtilis delta subunit of RNA polymerase== | ||
<StructureSection load='2krc' size='340' side='right'caption='[[2krc]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2krc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRC FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2krc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krc OCA], [https://pdbe.org/2krc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2krc RCSB], [https://www.ebi.ac.uk/pdbsum/2krc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2krc ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RPOE_BACSU RPOE_BACSU] Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling. May function in sigma factor switching. It displaces RNA bound to RNA polymerase in a binary complex. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kr/2krc_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2krc ConSurf]. | |||
<div style="clear:both"></div> | |||
== | ==See Also== | ||
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
< | |||
[[Category: Bacillus subtilis]] | [[Category: Bacillus subtilis]] | ||
[[Category: Jonak | [[Category: Large Structures]] | ||
[[Category: Krasny | [[Category: Jonak J]] | ||
[[Category: Motackova | [[Category: Krasny L]] | ||
[[Category: Novacek | [[Category: Motackova V]] | ||
[[Category: Padrta | [[Category: Novacek J]] | ||
[[Category: Sanderova | [[Category: Padrta P]] | ||
[[Category: Sklenar | [[Category: Sanderova H]] | ||
[[Category: Svenkova | [[Category: Sklenar V]] | ||
[[Category: Zidek | [[Category: Svenkova A]] | ||
[[Category: Zidek L]] | |||
Latest revision as of 19:13, 29 May 2024
Solution structure of the N-terminal domain of Bacillus subtilis delta subunit of RNA polymerase
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