Chymotrypsin 3D structures: Difference between revisions

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New page: == 3D Structures of Chymotrypsin == Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} The Chy precursor is the inactive '''chymotrypsinogen''' (Chygen) which ...
 
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**[[4h4f]] – hChyC +Elgin C - human<br />
**[[4h4f]] – hChyC +Elgin C - human<br />
**[[1cbw]], [[1mtn]] - bChy+BPTI <br />
**[[1cbw]], [[1mtn]], [[7qiq]] - bChy+BPTI <br />
**[[1t7c]], [[1t8l]], [[1t8m]], [[1t8n]], [[1t8o]] – bChyA+P1  BPTI variants<br />
**[[1t7c]], [[1t8l]], [[1t8m]], [[1t8n]], [[1t8o]] – bChyA+P1  BPTI variants<br />
**[[1oxg]] – bChyA+autolysis peptide<br />
**[[1oxg]] – bChyA+autolysis peptide<br />
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**[[1acb]] – bChy+Elgin C <br />
**[[1acb]] – bChy+Elgin C <br />
**[[1cho]], [[1hja]] – bChyA+turkey ovomucoid third domain <br />
**[[1cho]], [[1hja]] – bChyA+turkey ovomucoid third domain <br />
**[[7jrx]] – bChy + kunitz-type inhibitor<br />


* α-chymotrypsin + inhibitors  
* α-chymotrypsin + inhibitors  


**[[3bg4]] – ChyA chain A+guamerin <br />
**[[3bg4]] – bChyA chain A+guamerin <br />
**[[2p8o]] - bChyA chain A+benzohydroxamic acid/vanadate <br />
**[[2p8o]] - bChyA chain A+benzohydroxamic acid/vanadate <br />
**[[1eq9]] – Chy+PMSF – fire ant <br />
**[[2cha]] – bChyA+p-sulfinotoluene<br />
**[[2cha]] – bChyA+p-sulfinotoluene<br />
**[[6cha]] – bChyA+phenylethane boronic acid <br />
**[[6cha]] – bChyA+phenylethane boronic acid <br />
**[[1eq9]] – Chy+PMSF – fire ant <br />


* γ-Chymotrypsin + inhibitors  
* γ-Chymotrypsin + inhibitors  
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* Native Chymotrypsinogen  
* Native Chymotrypsinogen  


**[[2cga]], [[1chg]], [[1ex3]] – bChygenA<br />
**[[2cga]], [[1chg]], [[1ex3]], [[7kty]], [[7ktz]], [[7ku0]], [[7ku1]], [[7ku2]], [[7ku3]] – bChygenA<br />
**[[2jet]] – rChygenB chain A,B  <br />
**[[2jet]] – rChygenB chain A,B  <br />


* Chymotrypsinogen +  inhibitors  
* Chymotrypsinogen +  inhibitors  


**[[1gl0]], [[1gli]] – ChygenA+PMP_D2v – ''Locusta migratoria''<br />
**[[1k2i]] -  bChygenA+7-hydroxycoumarin<br />
**[[1k2i]] -  bChygenA+7-hydroxycoumarin<br />
**[[2y6t]] – bChygenA + ecotin<br />
**[[2y6t]] – bChygenA + ecotin<br />
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**[[3ru4]] - bChygenA + trypsin + Bowman-Birk inhibitor<br />
**[[3ru4]] - bChygenA + trypsin + Bowman-Birk inhibitor<br />
**[[1pyt]] – bChygenC + procarboxipeptidase + proproteinase<br />
**[[1pyt]] – bChygenC + procarboxipeptidase + proproteinase<br />
**[[7qir]], [[7qis]], [[7qit]] - bChygenA + BPTI<br />
**[[1gl0]], [[1gli]] – ChygenA+PMP_D2v – locust<br />
}}
}}


[[Category:Topic Page]]
[[Category:Topic Page]]

Latest revision as of 10:09, 28 January 2025

3D Structures of Chymotrypsin

Updated on 28-January-2025

The Chy precursor is the inactive chymotrypsinogen (Chygen) which gets cleaved 3 times by trypsin and chymotrypsin losing a 4 amino acid long peptide to become the active Chy. γ-Chy is a covalent acyl adduct of α-Chy. δ-Chy results when Chygen is cleaved only twice.

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Michal Harel