9bu4: Difference between revisions

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'''Unreleased structure'''


The entry 9bu4 is ON HOLD
==Crystal structure of an MKP5 mutant, Y435W, in complex with an allosteric inhibitor==
 
<StructureSection load='9bu4' size='340' side='right'caption='[[9bu4]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
Authors: Manjula, R., Bennett, A.M., Lolis, E.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9bu4]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9BU4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9BU4 FirstGlance]. <br>
Description: Crystal Structure of an MKP5 mutant, Y435W, in complex with an allosteric inhibitor
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CJA:3,3-dimethyl-1-[(9-methylsulfanyl-5,6-dihydrothieno[3,4-h]quinazolin-2-yl)sulfanyl]butan-2-one'>CJA</scene></td></tr>
[[Category: Manjula, R]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9bu4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9bu4 OCA], [https://pdbe.org/9bu4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9bu4 RCSB], [https://www.ebi.ac.uk/pdbsum/9bu4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9bu4 ProSAT]</span></td></tr>
[[Category: Lolis, E]]
</table>
[[Category: Bennett, A.M]]
== Function ==
[https://www.uniprot.org/uniprot/DUS10_HUMAN DUS10_HUMAN] Protein phosphatase involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily.<ref>PMID:22375048</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Bennett AM]]
[[Category: Lolis E]]
[[Category: Manjula R]]
Retrieved from "https://proteopedia.org/9bu4"