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Created by Lori Mathis
Created by Lori Mathis


1eve is a protein that is a drug used to prevent Alzheimer disease. The <scene name='Sandbox29/1eve/1'>overall structure</scene> of 1EVE contains a <scene name='Sandbox29/Evebeta/1'>beta sheet</scene> section with 15 sheets and 16 <scene name='Sandbox29/Evealpha/1'>alpha helices</scene>.  1eve is a fairly standard molecule in the sense that the  
1eve is a protein that is a drug used to prevent Alzheimer disease. The <scene name='Sandbox29/1eve/1'>overall structure</scene> of 1EVE contains 2 types of amphipathic elements; 15 <scene name='Sandbox29/Evebeta/1'>beta sheets</scene> and 16 <scene name='Sandbox29/Evealpha/1'>alpha helices</scene>.  1eve is a fairly standard molecule in the sense that the  
<scene name='Sandbox29/Hydrophobic/1'>hydrophic</scene> aspects of the protein are well-maintained on the inside, while the hydrophillic portions are around the outside. 1eve has an active name called Acetylcholinesterase, which has a ligand called Aricept. 1eve is considered an AChE inhibitor, in which it has a high affinity for. The overall protein itself was created by a Japanese corporation called the Eisai Company.
<scene name='Sandbox29/Hydrophobic/1'>hydrophic</scene> aspects of the protein are well-maintained on the inside, while the hydrophillic portions are around the outside. 1eve has an active name called Acetylcholinesterase, which has a ligand called Aricept. There is an
<scene name='Sandbox29/Active_site/1'>active site</scene> in the middle of the molecule.  1eve is considered an AChE inhibitor, in which it has a high affinity for. The overall protein itself was created by a Japanese corporation called the Eisai Company.


{{STRUCTURE_1eve |  PDB=1eve  |  SCENE=  }}
{{STRUCTURE_1eve |  PDB=1eve  |  SCENE=  }}
Reference to the Proteopedia pages dedicated to 1EVE, contributors are Eran Hodis, Joel L. Sussman, OCA, Wayne Decatur

Latest revision as of 23:59, 24 March 2009

1EVE

This sandbox is in use until June 1, 2009 for UMass Chemistry 490a. Others please do not edit this page. Thanks!


Created by Lori Mathis

1eve is a protein that is a drug used to prevent Alzheimer disease. The overall structure of 1EVE contains 2 types of amphipathic elements; 15 beta sheets and 16 alpha helices. 1eve is a fairly standard molecule in the sense that the hydrophic aspects of the protein are well-maintained on the inside, while the hydrophillic portions are around the outside. 1eve has an active name called Acetylcholinesterase, which has a ligand called Aricept. There is an active site in the middle of the molecule. 1eve is considered an AChE inhibitor, in which it has a high affinity for. The overall protein itself was created by a Japanese corporation called the Eisai Company.


Drag the structure with the mouse to rotate
1eve, resolution 2.50Å (default scene)
Ligands: E20, NAG
Activity: Acetylcholinesterase, with EC number 3.1.1.7
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Reference to the Proteopedia pages dedicated to 1EVE, contributors are Eran Hodis, Joel L. Sussman, OCA, Wayne Decatur

Retrieved from "https://proteopedia.org/index.php?title=Sandbox29&oldid=940054"