2wwe: Difference between revisions
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New page: '''Unreleased structure''' The entry 2wwe is ON HOLD Authors: ROOS, A.K., TRESAUGUES, L., ARROWSMITH, C.H., BERGLUND, H., BOUNTRA, C., COLLINS, R., EDWARDS, A.M., FLODIN, S., FLORES, A.... |
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==Crystal structure of the phox homology domain of human phosphoinositide-3-kinase-C2-gamma== | |||
<StructureSection load='2wwe' size='340' side='right'caption='[[2wwe]], [[Resolution|resolution]] 1.25Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2wwe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WWE FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wwe OCA], [https://pdbe.org/2wwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wwe RCSB], [https://www.ebi.ac.uk/pdbsum/2wwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wwe ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/P3C2G_HUMAN P3C2G_HUMAN] Generates phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that act as second messengers (By similarity). May play a role in SDF1A-stimulated chemotaxis (By similarity).[UniProtKB:O70167][UniProtKB:O70173] | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ww/2wwe_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wwe ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Phosphoinositide 3-kinase 3D structures|Phosphoinositide 3-kinase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arrowsmith CH]] | |||
[[Category: Berglund H]] | |||
[[Category: Bountra C]] | |||
[[Category: Collins R]] | |||
[[Category: Edwards AM]] | |||
[[Category: Flodin S]] | |||
[[Category: Flores A]] | |||
[[Category: Graslund S]] | |||
[[Category: Hammarstrom M]] | |||
[[Category: Johansson A]] | |||
[[Category: Johansson I]] | |||
[[Category: Kallas A]] | |||
[[Category: Karlberg T]] | |||
[[Category: Kotyenova T]] | |||
[[Category: Kotzch A]] | |||
[[Category: Kraulis P]] | |||
[[Category: Markova N]] | |||
[[Category: Moche M]] | |||
[[Category: Nielsen TK]] | |||
[[Category: Nordlund P]] | |||
[[Category: Nyman T]] | |||
[[Category: Persson C]] | |||
[[Category: Roos AK]] | |||
[[Category: Schuler H]] | |||
[[Category: Schutz P]] | |||
[[Category: Siponen MI]] | |||
[[Category: Svensson L]] | |||
[[Category: Thorsell AG]] | |||
[[Category: Tresaugues L]] | |||
[[Category: Van Der Berg S]] | |||
[[Category: Wahlberg E]] | |||
[[Category: Weigelt J]] | |||
[[Category: Welin M]] | |||
[[Category: Wisniewska M]] | |||
Latest revision as of 10:18, 20 December 2023
Crystal structure of the phox homology domain of human phosphoinositide-3-kinase-C2-gamma
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Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Homo sapiens
- Large Structures
- Arrowsmith CH
- Berglund H
- Bountra C
- Collins R
- Edwards AM
- Flodin S
- Flores A
- Graslund S
- Hammarstrom M
- Johansson A
- Johansson I
- Kallas A
- Karlberg T
- Kotyenova T
- Kotzch A
- Kraulis P
- Markova N
- Moche M
- Nielsen TK
- Nordlund P
- Nyman T
- Persson C
- Roos AK
- Schuler H
- Schutz P
- Siponen MI
- Svensson L
- Thorsell AG
- Tresaugues L
- Van Der Berg S
- Wahlberg E
- Weigelt J
- Welin M
- Wisniewska M
