3ga7: Difference between revisions
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==1.55 Angstrom Crystal Structure of an Acetyl Esterase from Salmonella typhimurium== | |||
<StructureSection load='3ga7' size='340' side='right'caption='[[3ga7]], [[Resolution|resolution]] 1.55Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3ga7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GA7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GA7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ga7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ga7 OCA], [https://pdbe.org/3ga7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ga7 RCSB], [https://www.ebi.ac.uk/pdbsum/3ga7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ga7 ProSAT], [https://www.topsan.org/Proteins/CSGID/3ga7 TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/AES_SALTY AES_SALTY] Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity (By similarity). | |||
== Evolutionary Conservation == | |||
== | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | |||
[ | <jmolCheckbox> | ||
[[ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ga/3ga7_consurf.spt"</scriptWhenChecked> | ||
[[ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
[[ | <text>to colour the structure by Evolutionary Conservation</text> | ||
[[ | </jmolCheckbox> | ||
[ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ga7 ConSurf]. | ||
[[ | <div style="clear:both"></div> | ||
[ | __TOC__ | ||
[ | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]] | ||
[[Category: | [[Category: Anderson WF]] | ||
[[Category: | [[Category: Brunzelle J]] | ||
[[Category: | [[Category: Minasov G]] | ||
[[Category: | [[Category: Onopriyenko O]] | ||
[[Category: | [[Category: Peterson SN]] | ||
[[Category: | [[Category: Savchenko A]] | ||
[[Category: | [[Category: Skarina T]] | ||
[[Category: | [[Category: Wawrzak Z]] | ||
Latest revision as of 05:50, 17 October 2024
1.55 Angstrom Crystal Structure of an Acetyl Esterase from Salmonella typhimurium
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