3km0: Difference between revisions
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New page: '''Unreleased structure''' The entry 3km0 is ON HOLD until sometime in the future Authors: Mazumdar, M., Lin, S.-X. Description: 17betaHSD1 in complex with 3beta-diol ''Page seeded by... |
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==17betaHSD1 in complex with 3beta-diol== | |||
<StructureSection load='3km0' size='340' side='right'caption='[[3km0]], [[Resolution|resolution]] 2.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3km0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KM0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KM0 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AOM:5-ALPHA-ANDROSTANE-3-BETA,17BETA-DIOL'>AOM</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3km0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3km0 OCA], [https://pdbe.org/3km0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3km0 RCSB], [https://www.ebi.ac.uk/pdbsum/3km0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3km0 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DHB1_HUMAN DHB1_HUMAN] Favors the reduction of estrogens and androgens. Also has 20-alpha-HSD activity. Uses preferentially NADH. | |||
==See Also== | |||
*[[Hydroxysteroid dehydrogenase 3D structures|Hydroxysteroid dehydrogenase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Lin S-X]] | |||
[[Category: Mazumdar M]] | |||
Latest revision as of 10:17, 21 February 2024
17betaHSD1 in complex with 3beta-diol
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