2kyl: Difference between revisions
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New page: '''Unreleased structure''' The entry 2kyl is ON HOLD Authors: TERRIEN, E., WOLFF, N., CORDIER, F., SIMENEL, C., LAFON, M., DELEPIERRE, M. Description: Solution structure of MAST2-PDZ c... |
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==Solution structure of MAST2-PDZ complexed with the C-terminus of PTEN== | |||
<StructureSection load='2kyl' size='340' side='right'caption='[[2kyl]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2kyl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KYL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KYL FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kyl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kyl OCA], [https://pdbe.org/2kyl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kyl RCSB], [https://www.ebi.ac.uk/pdbsum/2kyl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kyl ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MAST2_HUMAN MAST2_HUMAN] Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity).[UniProtKB:Q60592] | |||
==See Also== | |||
*[[Microtubule-associated serine/threonine kinase|Microtubule-associated serine/threonine kinase]] | |||
*[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Cordier F]] | |||
[[Category: Delepierre M]] | |||
[[Category: Lafon M]] | |||
[[Category: Simenel C]] | |||
[[Category: Terrien E]] | |||
[[Category: Wolff N]] | |||
Latest revision as of 05:37, 15 May 2024
Solution structure of MAST2-PDZ complexed with the C-terminus of PTEN
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