3q90: Difference between revisions
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New page: '''Unreleased structure''' The entry 3q90 is ON HOLD Authors: Welin, M., Tresaugues, L., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Ekblad, T., Flodin, S.,... |
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==Crystal structure of the NTF2 domain of Ras GTPase-activating protein-binding protein 1== | |||
<StructureSection load='3q90' size='340' side='right'caption='[[3q90]], [[Resolution|resolution]] 1.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3q90]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q90 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q90 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q90 OCA], [https://pdbe.org/3q90 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q90 RCSB], [https://www.ebi.ac.uk/pdbsum/3q90 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q90 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/G3BP1_HUMAN G3BP1_HUMAN] May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.<ref>PMID:9889278</ref> <ref>PMID:11604510</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arrowsmith CH]] | |||
[[Category: Berglund H]] | |||
[[Category: Bountra C]] | |||
[[Category: Collins R]] | |||
[[Category: Edwards AM]] | |||
[[Category: Ekblad T]] | |||
[[Category: Flodin S]] | |||
[[Category: Flores A]] | |||
[[Category: Graslund S]] | |||
[[Category: Hammarstrom M]] | |||
[[Category: Johansson I]] | |||
[[Category: Karlberg T]] | |||
[[Category: Kol S]] | |||
[[Category: Kotenyova T]] | |||
[[Category: Kouznetsova E]] | |||
[[Category: Moche M]] | |||
[[Category: Nordlund P]] | |||
[[Category: Nyman T]] | |||
[[Category: Persson C]] | |||
[[Category: Schuler H]] | |||
[[Category: Schutz P]] | |||
[[Category: Siponen MI]] | |||
[[Category: Thorsell AG]] | |||
[[Category: Tresaugues L]] | |||
[[Category: Van Der Berg S]] | |||
[[Category: Wahlberg E]] | |||
[[Category: Weigelt J]] | |||
[[Category: Welin M]] | |||
Latest revision as of 11:37, 14 March 2024
Crystal structure of the NTF2 domain of Ras GTPase-activating protein-binding protein 1
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