3q90: Difference between revisions

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'''Unreleased structure'''


The entry 3q90 is ON HOLD
==Crystal structure of the NTF2 domain of Ras GTPase-activating protein-binding protein 1==
 
<StructureSection load='3q90' size='340' side='right'caption='[[3q90]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
Authors: Welin, M., Tresaugues, L., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Ekblad, T., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Karlberg, T., Kol, S., Kotenyova, T., Kouznetsova, E., Moche, M., Nyman, T., Persson, C., Schuler, H., Schutz, P., Siponen, M.I., Thorsell, A.G., Van Der Berg, S., Wahlberg, E., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3q90]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q90 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q90 FirstGlance]. <br>
Description: Crystal structure of the NTF2 domain of Ras GTPase-activating protein-binding protein 1
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q90 OCA], [https://pdbe.org/3q90 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q90 RCSB], [https://www.ebi.ac.uk/pdbsum/3q90 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q90 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/G3BP1_HUMAN G3BP1_HUMAN] May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.<ref>PMID:9889278</ref> <ref>PMID:11604510</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Berglund H]]
[[Category: Bountra C]]
[[Category: Collins R]]
[[Category: Edwards AM]]
[[Category: Ekblad T]]
[[Category: Flodin S]]
[[Category: Flores A]]
[[Category: Graslund S]]
[[Category: Hammarstrom M]]
[[Category: Johansson I]]
[[Category: Karlberg T]]
[[Category: Kol S]]
[[Category: Kotenyova T]]
[[Category: Kouznetsova E]]
[[Category: Moche M]]
[[Category: Nordlund P]]
[[Category: Nyman T]]
[[Category: Persson C]]
[[Category: Schuler H]]
[[Category: Schutz P]]
[[Category: Siponen MI]]
[[Category: Thorsell AG]]
[[Category: Tresaugues L]]
[[Category: Van Der Berg S]]
[[Category: Wahlberg E]]
[[Category: Weigelt J]]
[[Category: Welin M]]