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[[Image:2dtn.gif|left|200px]]<br /><applet load="2dtn" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2dtn, resolution 2.5&Aring;" />
'''Crystal structure of Helicobacter pylori undecaprenyl pyrophosphate synthase complexed with pyrophosphate'''<br />


==About this Structure==
==Crystal structure of Helicobacter pylori undecaprenyl pyrophosphate synthase complexed with pyrophosphate==
2DTN is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori] with <scene name='pdbligand=DPO:'>DPO</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Di-trans,poly-cis-decaprenylcistransferase Di-trans,poly-cis-decaprenylcistransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.31 2.5.1.31] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DTN OCA].  
<StructureSection load='2dtn' size='340' side='right'caption='[[2dtn]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
[[Category: Di-trans,poly-cis-decaprenylcistransferase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[2dtn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DTN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DTN FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPO:DIPHOSPHATE'>DPO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dtn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dtn OCA], [https://pdbe.org/2dtn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dtn RCSB], [https://www.ebi.ac.uk/pdbsum/2dtn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dtn ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ISPT_HELPY ISPT_HELPY] Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dt/2dtn_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dtn ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Undecaprenyl pyrophosphate synthase|Undecaprenyl pyrophosphate synthase]]
__TOC__
</StructureSection>
[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
[[Category: Protein complex]]
[[Category: Large Structures]]
[[Category: Chen, C.L.]]
[[Category: Chen CL]]
[[Category: Guo, R.T.]]
[[Category: Guo RT]]
[[Category: Ko, T.P.]]
[[Category: Ko TP]]
[[Category: Kuo, C.J.]]
[[Category: Kuo CJ]]
[[Category: Liang, P.H.]]
[[Category: Liang PH]]
[[Category: Wang, A.H.J.]]
[[Category: Wang AH-J]]
[[Category: DPO]]
[[Category: cis prenyltransferase]]
[[Category: crystal structure]]
[[Category: helicobacter pylori]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 14:44:07 2008''

Latest revision as of 08:29, 25 October 2023

Crystal structure of Helicobacter pylori undecaprenyl pyrophosphate synthase complexed with pyrophosphate

2dtn, resolution 2.50Å

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