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[[Image:1vty.jpg|left|200px]]


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==Crystal structure of a Z-DNA fragment containing thymine/2-aminoadenine base pairs==
The line below this paragraph, containing "STRUCTURE_1vty", creates the "Structure Box" on the page.
<StructureSection load='1vty' size='340' side='right'caption='[[1vty]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1vty]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VTY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VTY FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1AP:2,6-DIAMINOPURINE+NUCLEOTIDE'>1AP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
{{STRUCTURE_1vty|  PDB=1vty  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vty OCA], [https://pdbe.org/1vty PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vty RCSB], [https://www.ebi.ac.uk/pdbsum/1vty PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vty ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The Z-DNA structure has been shown to form in two crystals made from self-complementary DNA hexamers d(CGTDCG) and d(CDCGTG) which contain thymine/2-aminoadenine (TD) base pairs. The latter structure has been solved and refined to 1.3 A resolution and it shows only small conformational changes due to the introduction of the TD base pairs in comparison with the structure of d(CG)3. Spectroscopic studies with these compounds demonstrate that DNA molecules containing 2-aminoadenine residues form Z-DNA slightly more easily than do those containing adenine nucleotides, but not as readily as the parent sequence containing only guanine-cytosine base pairs.


===Crystal structure of a Z-DNA fragment containing thymine/2-aminoadenine base pairs===
Crystal structure of a Z-DNA fragment containing thymine/2-aminoadenine base pairs.,Coll M, Wang AH, van der Marel GA, van Boom JH, Rich A J Biomol Struct Dyn. 1986 Oct;4(2):157-72. doi: 10.1080/07391102.1986.10506337. PMID:3271437<ref>PMID:3271437</ref>


 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
==About this Structure==
</div>
[[1vty]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VTY OCA].
<div class="pdbe-citations 1vty" style="background-color:#fffaf0;"></div>
[[Category: Boom, J H.Van.]]
== References ==
[[Category: Coll, M.]]
<references/>
[[Category: Marel, G A.Van Der.]]
__TOC__
[[Category: Rich, A.]]
</StructureSection>
[[Category: Wang, A H.J.]]
[[Category: Large Structures]]
[[Category: Dna]]
[[Category: Synthetic construct]]
[[Category: Double helix]]
[[Category: Coll M]]
[[Category: Modified]]
[[Category: Rich A]]
[[Category: Z-dna]]
[[Category: Van Boom JH]]
[[Category: Van Der Marel GA]]
[[Category: Wang AH-J]]