Response regulator: Difference between revisions
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Michal Harel (talk | contribs) New page: {{STRUCTURE_1zg1| PDB=1zg1 | SIZE=400| SCENE= |right|CAPTION=E. coli response regulator NarL complex with DNA, 1zg1 }} '''Response regulators''' (RR) are part of the two-component s... |
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<StructureSection load='1kgs' size='350' side='right' scene='' caption='Se-Met DNA-binding response regulator D complex with thiocyanate, [[1kgs]]'> | |||
'''Response regulators''' (RR) are part of the two-component signal transduction systems which enable bacteria to sense and respond to a wide range of environments. | '''Response regulators''' (RR) are part of the two-component signal transduction systems which enable bacteria to sense and respond to a wide range of environments. | ||
Two-component RR is a complex of histidine kinase (sensor protein SP) and RR. The RR act as phosphorylation-activated switches. Most RR consist of N terminal | Two-component RR is a complex of histidine kinase (sensor protein SP) and RR. The RR act as phosphorylation-activated switches. Most RR consist of N terminal which is the signal receiving domain and C terminal which is the DNA-binding domain (DBD). | ||
*'''RR CheY''' is a chemotaxis response regulator in bacteria see [[Chemotaxis protein]].<ref>PMID:14563873</ref>. <br /> | |||
*'''RR Spo0''' is the sporulation response regulator<ref>PMID:12829280</ref>. <br /> | |||
*'''RR PleD''' is required in loss of motility<ref>PMID:7592388</ref>. For details see [[PleD activation]], [[PleD allosteric product inhibition]], [[PleD catalysis]] and [[Response regulator PLED in complex with C-di-GMP]]<br /> | |||
*'''RR PhoP''' is important for survival under conditions of macrophage-induced stress<ref>PMID:21634789</ref>. For details see [[PhoP Regulatory Domain]] and [[PhoP-PhoQ]]<br /> | |||
*'''Photosynthetic apparatus RR''' in ''Rhodobacter sphaeroides'' is involved in the transduction of signals which monitor oxygen levels. <ref>PMID:8955382</ref>. For details see [[PrrA in Rhodobacter sphaeroides]] <br /> | |||
*'''RR WspR''' couples the chemosensory Wsp pathway to the overproduction of acetylated cellulase <ref>PMID:17379708</ref>. For details see [[WspR]].<br /> | |||
*'''Redox RR''' is DNA-sequence specific. It controls transcription as a result of its phosphorylation by a redox sensor<ref>PMID:8405457</ref>. <br /> | |||
For '''iron response regulator Irr''' see [[Irr]]. | |||
== 3D Structures of response regulator == | == 3D Structures of response regulator == | ||
[[Response regulator 3D structure]] | |||
</StructureSection> | |||
== References == | |||
<references/> | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Latest revision as of 12:17, 9 December 2019
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References
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky
