3shi: Difference between revisions

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[[Image:3shi.png|left|200px]]


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==Crystal structure of human MMP1 catalytic domain at 2.2 A resolution==
The line below this paragraph, containing "STRUCTURE_3shi", creates the "Structure Box" on the page.
<StructureSection load='3shi' size='340' side='right'caption='[[3shi]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3shi]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SHI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SHI FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_3shi|  PDB=3shi  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3shi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3shi OCA], [https://pdbe.org/3shi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3shi RCSB], [https://www.ebi.ac.uk/pdbsum/3shi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3shi ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MMP1_HUMAN MMP1_HUMAN] Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.<ref>PMID:1645757</ref>


===Crystal structure of human MMP1 catalytic domain at 2.2 A resolution===
==See Also==
 
*[[Matrix metalloproteinase 3D structures|Matrix metalloproteinase 3D structures]]
 
== References ==
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<references/>
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(as it appears on PubMed at http://www.pubmed.gov), where 21945315 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21945315}}
 
==About this Structure==
[[3shi]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SHI OCA].
 
==Reference==
<ref group="xtra">PMID:021945315</ref><ref group="xtra">PMID:008031754</ref><ref group="xtra">PMID:008090713</ref><ref group="xtra">PMID:010074939</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Interstitial collagenase]]
[[Category: Large Structures]]
[[Category: Bertini, I.]]
[[Category: Bertini I]]
[[Category: Calderone, V.]]
[[Category: Calderone V]]
[[Category: Cerofolini, L.]]
[[Category: Cerofolini L]]
[[Category: Fragai, M.]]
[[Category: Fragai M]]
[[Category: Geraldes, C F.G C.]]
[[Category: Geraldes CFGC]]
[[Category: Hermann, P.]]
[[Category: Hermann P]]
[[Category: Luchinat, C.]]
[[Category: Luchinat C]]
[[Category: Parigi, G.]]
[[Category: Parigi G]]
[[Category: Teixeira, J.]]
[[Category: Teixeira J]]
[[Category: Hydrolase]]
[[Category: Lanthanide]]
[[Category: Matrix metalloproteinase]]
[[Category: Paramagnetic restraint]]
[[Category: Paramagnetic tag]]
[[Category: Protein refinement]]
[[Category: Residual dipolar coupling]]

Latest revision as of 12:56, 14 March 2024

Crystal structure of human MMP1 catalytic domain at 2.2 A resolution

3shi, resolution 2.20Å

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