Matrix metalloproteinase 3D structures

3D structures of matrix metalloproteinase

Updated on 15-December-2025

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• MMP1 interstitial or fibroblast collagenase
  • 1su3 – pro-hMMP – human
    
  • 1cge, 1cgf, 1hfc, 3shi - hMMP catalytic domain 100-466
    
  • 2clt – hMMP catalytic domain (mutant)
    
  • 1cgl, 2tcl, 966c - hMMP catalytic domain + inhibitor
    
  • 1ayk, 2ayk, 3ayk, 4ayk - hMMP catalytic domain - NMR
    
  • 4auo - hMMP catalytic domain + collagen peptide
    
  • 1fbl – MMP - pig
• MMP2 gelatinase-A
  • 1ck7, 1qib - hMMP catalytic domain (mutant)
    
  • 1rtg - hMMP hemopexin-like domain 451-660
    
  • 1ks0 – hMMP first fibronectin type II domain 223-282– NMR
    
  • 1cxw - hMMP second fibronectin type II domain 278-336– NMR
    
  • 1j7m - hMMP third fibronectin type II domain 337-394 (mutant) – NMR
    
  • 1gen – hMMP C terminal
    
  • 1eak – pro-hMMP catalytic domain (mutant) + peptide inhibitor
    
  • 3ayu, 7xgj - hMMP catalytic domain (mutant) + peptide inhibitor
    
  • 7xjo, 8h78 - hMMP catalytic domain + inhibitor
    
  • 1eub, 1hov - hMMP catalytic domain + inhibitor– NMR
    
  • 1gxd – pro-hMMP (mutant) + TIMP-2
• MMP3 stromelysin 1
  • 1cqr, 1qia, 1qic, 1slm - hMMP catalytic domain
    
  • 1b3d, 1b8y, 1biw, 1bqo, 1c3i, 1caq, 1ciz, 1d5j, 1d7x, 1d8f, 1d8m, 1g05, 1g49, 1g4k, 1hfs, 1hy7, 1ums, 1umt, 1usn, 2d1n, 2d1o, 2ow9, 2srt, 2usn, 3ohl, 3oho, 4dpe, 4g9l, 4ja1, 5uwk, 5uwl, 5uwm, 5uwn - hMMP catalytic domain + inhibitor
    
  • 7s7l, 7s7m – hMMP catalytic domain + MMP inhibitor
    
  • 1c8t - hMMP catalytic domain (mutant) + inhibitor
    
  • 1uea, 6mav, 6n9d - hMMP catalytic domain + TIMP-1
    
  • 1oo9 - hMMP catalytic domain + TIMP-1 N terminal
    
  • 1bm6, 1sln, 2jt5, 2jt6, 2jnp, 3usn - hMMP catalytic domain + inhibitor – NMR
    
• MMP7 matrilysin
  • 1mmp, 1mmq, 1mmr, 2ddy, 2y6c, 2y6d – hMMP catalytic domain + inhibitor
    
  • 7wxx, 8k4z - hMMP catalytic domain + peptide inhibitor
    
  • 8jud, 8juf, 8jug - hMMP catalytic domain (mutant) + peptide inhibitor
    
  • 2mze – hpro-MMP (mutant) - NMR
    
  • 2mzh, 2mzi – hpro-MMP (mutant) + membrane bilayer - NMR
    
  • 5ue2, 5ue5 – hpro-MMP (mutant) + heparin - NMR
    
• MMP8 neutrophil collagenase
  • 1bzs, 1mnc, 2oy4 - hMMP catalytic domain
    
  • 1a85, 1i76, 1jh1, 1jj9, 1kbc, 1mmb, 1zp5, 1zs0, 1zvx, 3dng, 3dpe, 3dpf, 3tt4, 4qkz, 5h8x – hMMP catalytic domain + inhibitor
    
  • 1i73, 1jan, 1jao, 1jap, 1jaq, 2oy2 - hMMP catalytic domain + peptide inhibitor
    
  • 1a86 - hMMP catalytic domain + aspartate-based inhibitor
• MMP9 gelatinase-B
  • 1l6j - pro-hMMP
    
  • 1itv – hMMP haemopexin-like domain
    
  • 1gkc, 4wzv, 4xct, 5cuh, 5i12, 5th6 - hMMP catalytic domain + inhibitor
    
  • 5ue3, 5ue4, 8k5v, 8k5w, 8k5x, 8k5y – pro-hMMP catalytic domain + inhibitor
    
  • 1gkd, 2ow0, 2ow1, 2ow2, 2ovx, 2ovz, 4h1q, 4h2e, 4h3x, 4h82, 4hma, 6esm - hMMP catalytic domain (mutant) + inhibitor
    
  • 4jij, 4jqg - hMMP catalytic domain (mutant) + FRET substrate
    
  • 5th9 - hMMP catalytic domain + antibody
    
• MMP10 stromelysin 2
  • 9csx – pro-hMMP catalytic domain
    
  • 1q3a - hMMP catalytic domain (mutant)
    
  • 3v96, 4ilw - hMMP catalytic domain + metalloproteinase inhibitor
• MMP11 stromelysin 3
  • 1hv5 - hMMP catalytic domain + inhibitor
    
• MMP12 macrophage metalloelastase
  • 2oxu, 3ba0 - pro-hMMP
    
  • 2k9c, 2krj - hMMP catalytic domain – NMR
    
  • 1jiz, 1jk3, 2oxu - hMMP catalytic domain
    
  • 4ijo - hMMP catalytic domain (mutant)
    
  • 2poj - hMMP catalytic domain (mutant) - NMR
    
  • 2jxy - hMMP hemopexin-like domain - NMR
    
  • 1ros, 1utt, 1utz, 3n2u, 3n2v, 2wo8, 2wo9, 2woa, 3rts, 3rtt, 7ovy – hMMP catalytic domain + inhibitor
    
  • 1os2, 1os9, 1jk3, 1rmz, 1y93, 2hu6, 3ehx, 3ehy, 3f15, 3f16, 3f17, 3f18, 3f19, 3f1a, 3lik, 3lil, 3lir, 3ljg, 3lk8, 3lka, 3nx7, 3ts4, 3tsk, 3uvc, 4efs, 4gql, 4gr0, 4gr3, 4gr8, 4guy, 4h30, 4h49, 4h76, 4h84, 4io3, 5cxa, 5czm, 5d2b, 5d3c, 5i0l, 5i2z, 5i3m, 5i43, 5i4o, 5l79, 5l7f, 5lab, 5n5k, 5n5j, 6ekn, 6ela, 6enm, 6eox, 6rd0, 6rly - hMMP catalytic domain (mutant) + inhibitor
    
  • 2oxn, 2oxw, 2oxx - hMMP catalytic domain (mutant) + peptide
    
  • 2n8r - hMMP catalytic domain (mutant) + collagen peptide – NMR
    
  • 2k2g, 2z2d - hMMP catalytic domain + inhibitor - NMR
    
  • 2mlr, 2mls - hMMP catalytic domain + membrane billayer
    
  • 1ycm, 1z3j, 2w0d - hMMP catalytic domain (mutant) + inhibitor - NMR
    
  • 8b2n - hMMP catalytic domain + potempin A
    
• MMP13 collagenase 3
  • 1pex – hMMP hemopexin-like domain
    
  • 1fls, 1fm1, 1xuc, 1xud, 1xur, 1you, 1ztq, 2ozr, 2pjt, 2yig, 3elm, 3i7g, 3i7i, 3kec, 3kej, 3kek, 3kry, 3ljz, 3o2x, 3tvc, 3wv1, 3wv2, 3wv3, 3zxh, 456c, 4a7b, 4jp4, 4jpa, 4l19, 5b5o, 5b5p, 5bot, 5boy, 5bpa, 7ju8, 830c – hMMP catalytic domain + inhibitor
    
  • 2e2d - hMMP catalytic domain + TIMP-2
    
  • 4fu4, 4fvl, 4g0d - hMMP catalytic domain (mutant) + pro-domain peptide
    
  • 6hv2 - hMMP catalytic domain + peptide
    
  • 1cxv - MMP catalytic domain - mouse
    
• MMP14 Membrane T1
  • 3ma2 – hMMP residues 112-292 + TIMP-1 (mutant)
    
  • 1buv, 1bqq residues 112-292 hMMP + TIMP-2
    
  • 5h0u - hMMP residues 112-292 + polyHis
    
  • 3c7x – hMMP hemopexin domain residues 316-511
    
  • 6clz, 6cm1 – hMMP hemopexin domain + apolipoprotein
    
  • 2mqs - hMMP + collagen
    
• MMP16 Membrane T3
  • 1rm8 - hMMP catalytic domain + inhibitor
    
• MMP20 enamelysin
  • 2jsd - hMMP catalytic domain + inhibitor - NMR
    
• MMP23 CA-MMP
  • 2k72 – hMMP residues 254-290 - NMR
    
• MMP adamalysin
  • 1iag – MMP – diamondback rattlesnake
    
  • 3k7l - MMP - cobra
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel