3vk6: Difference between revisions
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New page: '''Unreleased structure''' The entry 3vk6 is ON HOLD Authors: Sivaraman, J, Manjeet, M Description: Crystal structure of a phosphotyrosine binding domain |
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==Crystal structure of a phosphotyrosine binding domain== | |||
<StructureSection load='3vk6' size='340' side='right'caption='[[3vk6]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3vk6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VK6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VK6 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vk6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vk6 OCA], [https://pdbe.org/3vk6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vk6 RCSB], [https://www.ebi.ac.uk/pdbsum/3vk6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vk6 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/HAKAI_MOUSE HAKAI_MOUSE] Promotes ubiquitination of several tyrosine-phosphorylated Src substrates, including CDH1, CTTN and DOK1. Targets CDH1 for endocytosis and degradation.<ref>PMID:11836526</ref> <ref>PMID:22252131</ref> | |||
==See Also== | |||
*[[Ubiquitin protein ligase 3D structures|Ubiquitin protein ligase 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Mukherjee M]] | |||
[[Category: Sivaraman J]] | |||
Latest revision as of 08:40, 20 March 2024
Crystal structure of a phosphotyrosine binding domain
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