3tnf: Difference between revisions

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[[Image:3tnf.png|left|200px]]


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==LidA from Legionella in complex with active Rab8a==
The line below this paragraph, containing "STRUCTURE_3tnf", creates the "Structure Box" on the page.
<StructureSection load='3tnf' size='340' side='right'caption='[[3tnf]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3tnf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila_str._Philadelphia_1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TNF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TNF FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
{{STRUCTURE_3tnf|  PDB=3tnf  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tnf OCA], [https://pdbe.org/3tnf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tnf RCSB], [https://www.ebi.ac.uk/pdbsum/3tnf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tnf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RAB8A_HUMAN RAB8A_HUMAN] May be involved in vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Together with MYO5B and RAB11A participates in epithelial cell polarization.<ref>PMID:20890297</ref> <ref>PMID:21282656</ref>


===LidA from Legionella in complex with active Rab8a===
==See Also==
 
*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]
 
== References ==
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{{ABSTRACT_PUBMED_22011575}}
 
==About this Structure==
[[3tnf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila_str._philadelphia_1 Legionella pneumophila subsp. pneumophila str. philadelphia 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TNF OCA].
 
==Reference==
<ref group="xtra">PMID:022011575</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Legionella pneumophila subsp. pneumophila str. philadelphia 1]]
[[Category: Large Structures]]
[[Category: Cichy, A L.]]
[[Category: Legionella pneumophila subsp. pneumophila str. Philadelphia 1]]
[[Category: Goody, R S.]]
[[Category: Cichy AL]]
[[Category: Itzen, A.]]
[[Category: Goody RS]]
[[Category: Schoebel, S.]]
[[Category: Itzen A]]
[[Category: Drra]]
[[Category: Schoebel S]]
[[Category: Er]]
[[Category: Gdp/gtp binding rab-binding]]
[[Category: Golgi]]
[[Category: Gtpase]]
[[Category: Lcv]]
[[Category: Legionella pneumophila]]
[[Category: Plasmamembrane]]
[[Category: Protein transport]]
[[Category: Rab-effector]]
[[Category: Rab8a]]
[[Category: Sidm]]
[[Category: Vesicle recuitment]]
[[Category: Vesicular trafficking]]
[[Category: Vesicular transport]]

Latest revision as of 10:10, 1 March 2024

LidA from Legionella in complex with active Rab8a

3tnf, resolution 2.50Å

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