2zrx: Difference between revisions

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[[Image:2zrx.png|left|200px]]


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==Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase in complex with FMN and DMAPP.==
The line below this paragraph, containing "STRUCTURE_2zrx", creates the "Structure Box" on the page.
<StructureSection load='2zrx' size='340' side='right'caption='[[2zrx]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2zrx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_shibatae Saccharolobus shibatae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZRX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZRX FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMA:DIMETHYLALLYL+DIPHOSPHATE'>DMA</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_2zrx| PDB=2zrx |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zrx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zrx OCA], [https://pdbe.org/2zrx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zrx RCSB], [https://www.ebi.ac.uk/pdbsum/2zrx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zrx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IDI2_SACSH IDI2_SACSH] Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).[HAMAP-Rule:MF_00354]<ref>PMID:19158086</ref> <ref>PMID:22158896</ref> <ref>PMID:22505674</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zr/2zrx_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zrx ConSurf].
<div style="clear:both"></div>


===Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase in complex with FMN and DMAPP.===
==See Also==
 
*[[Isopentenyl-diphosphate delta-isomerase|Isopentenyl-diphosphate delta-isomerase]]
 
== References ==
<!--  
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_19158086}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 19158086 is the PubMed ID number.
</StructureSection>
-->
[[Category: Large Structures]]
{{ABSTRACT_PUBMED_19158086}}
[[Category: Saccharolobus shibatae]]
 
[[Category: Hemmi H]]
==About this Structure==
[[Category: Ikeda Y]]
[[2zrx]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_shibatae Sulfolobus shibatae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZRX OCA].
[[Category: Kusunoki M]]
 
[[Category: Nakayama T]]
==Reference==
[[Category: Nishino T]]
<ref group="xtra">PMID:019158086</ref><references group="xtra"/>
[[Category: Sekiguchi S]]
[[Category: Isopentenyl-diphosphate Delta-isomerase]]
[[Category: Unno H]]
[[Category: Sulfolobus shibatae]]
[[Category: Yamashita S]]
[[Category: Hemmi, H.]]
[[Category: Yoshida N]]
[[Category: Ikeda, Y.]]
[[Category: Yoshimura T]]
[[Category: Kusunoki, M.]]
[[Category: Nakayama, T.]]
[[Category: Nishino, T.]]
[[Category: Sekiguchi, S.]]
[[Category: Unno, H.]]
[[Category: Yamashita, S.]]
[[Category: Yoshida, N.]]
[[Category: Yoshimura, T.]]
[[Category: Dmapp]]
[[Category: Flavoprotein]]
[[Category: Fmn]]
[[Category: Idi]]
[[Category: Isomerase]]
[[Category: Isopentenyl diphosphate isomerase]]
[[Category: Isoprene biosynthesis]]
[[Category: Nadp]]
[[Category: Type 2]]

Latest revision as of 13:58, 13 March 2024

Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase in complex with FMN and DMAPP.

2zrx, resolution 3.00Å

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