1vbj: Difference between revisions

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[[Image:1vbj.png|left|200px]]


<!--
==The crystal structure of prostaglandin F synthase from Trypanosoma brucei==
The line below this paragraph, containing "STRUCTURE_1vbj", creates the "Structure Box" on the page.
<StructureSection load='1vbj' size='340' side='right'caption='[[1vbj]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1vbj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VBJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VBJ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
{{STRUCTURE_1vbj| PDB=1vbj |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vbj OCA], [https://pdbe.org/1vbj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vbj RCSB], [https://www.ebi.ac.uk/pdbsum/1vbj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vbj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PGFS_TRYBB PGFS_TRYBB] Catalyzes the NADP-dependent formation of prostaglandin F2-alpha from prostaglandin H2. Has also aldo/ketoreductase activity towards the synthetic substrates 9,10-phenanthrenequinone and p-nitrobenzaldehyde.<ref>PMID:11067881</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vb/1vbj_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vbj ConSurf].
<div style="clear:both"></div>


===The crystal structure of prostaglandin F synthase from Trypanosoma brucei===
==See Also==
 
*[[Prostaglandin F synthase 3D structures|Prostaglandin F synthase 3D structures]]
 
== References ==
<!--
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_015845552}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 015845552 is the PubMed ID number.
</StructureSection>
-->
[[Category: Large Structures]]
{{ABSTRACT_PUBMED_015845552}}
 
==About this Structure==
[[1vbj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VBJ OCA].
 
==Reference==
<ref group="xtra">PMID:015845552</ref><references group="xtra"/>
[[Category: Prostaglandin-F synthase]]
[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]
[[Category: Inoue, T.]]
[[Category: Inoue T]]
[[Category: Oxidoreductase]]
[[Category: Tim barrel]]

Latest revision as of 00:01, 28 December 2023

The crystal structure of prostaglandin F synthase from Trypanosoma brucei

1vbj, resolution 2.10Å

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