2hfu: Difference between revisions

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[[Image:2hfu.png|left|200px]]


<!--
==Crystal structure of L. major mevalonate kinase in complex with R-mevalonate==
The line below this paragraph, containing "STRUCTURE_2hfu", creates the "Structure Box" on the page.
<StructureSection load='2hfu' size='340' side='right'caption='[[2hfu]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2hfu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HFU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HFU FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MEV:(R)-MEVALONATE'>MEV</scene></td></tr>
{{STRUCTURE_2hfu| PDB=2hfu |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hfu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hfu OCA], [https://pdbe.org/2hfu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hfu RCSB], [https://www.ebi.ac.uk/pdbsum/2hfu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hfu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q4Q6K7_LEIMA Q4Q6K7_LEIMA]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hf/2hfu_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hfu ConSurf].
<div style="clear:both"></div>


===Crystal structure of L. major mevalonate kinase in complex with R-mevalonate===
==See Also==
 
*[[Mevalonate kinase|Mevalonate kinase]]
 
__TOC__
<!--
</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_17397541}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 17397541 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_17397541}}
 
==About this Structure==
[[2hfu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HFU OCA].
 
==Reference==
<ref group="xtra">PMID:017397541</ref><references group="xtra"/>
[[Category: Leishmania major]]
[[Category: Leishmania major]]
[[Category: Mevalonate kinase]]
[[Category: Hunter WN]]
[[Category: Hunter, W N.]]
[[Category: Sgraja T]]
[[Category: Sgraja, T.]]
[[Category: Ghmp kinase]]
[[Category: Mevalonate kinase]]
[[Category: Transferase]]
[[Category: Trypanosomatid parasite]]

Latest revision as of 09:32, 14 February 2024

Crystal structure of L. major mevalonate kinase in complex with R-mevalonate

2hfu, resolution 2.00Å

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