3kyl: Difference between revisions

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[[Image:3kyl.png|left|200px]]


{{STRUCTURE_3kyl|  PDB=3kyl  |  SCENE=  }}
==Structure of the catalytic subunit of telomerase bound to its RNA template and telomeric DNA==
 
<StructureSection load='3kyl' size='340' side='right'caption='[[3kyl]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
===Structure of the catalytic subunit of telomerase bound to its RNA template and telomeric DNA===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3kyl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Tribolium_castaneum Tribolium castaneum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KYL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KYL FirstGlance]. <br>
{{ABSTRACT_PUBMED_20357774}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kyl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kyl OCA], [https://pdbe.org/3kyl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kyl RCSB], [https://www.ebi.ac.uk/pdbsum/3kyl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kyl ProSAT]</span></td></tr>
[[3kyl]] is a 2 chain structure of [[Reverse transcriptase]], [[Telomerase]] and [[Telomerase Reverse Transcriptase]] with sequence from [http://en.wikipedia.org/wiki/Tribolium_castaneum Tribolium castaneum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KYL OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q0QHL8_TRICA Q0QHL8_TRICA]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ky/3kyl_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kyl ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Reverse transcriptase|Reverse transcriptase]]
*[[Telomerase|Telomerase]]
*[[Telomerase|Telomerase]]
*[[Telomerase Reverse Transcriptase|Telomerase Reverse Transcriptase]]
*[[Telomerase 3D structures|Telomerase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:020357774</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Tribolium castaneum]]
[[Category: Tribolium castaneum]]
[[Category: Skordalakes, E.]]
[[Category: Skordalakes E]]
[[Category: Nucleic acid binding protein-dna-rna complex]]
[[Category: Protein-rna-dna complex]]
[[Category: Reverse transcriptase]]
[[Category: Rna-directed dna polymerase]]
[[Category: Telomerase]]

Latest revision as of 10:18, 21 February 2024

Structure of the catalytic subunit of telomerase bound to its RNA template and telomeric DNA

3kyl, resolution 2.70Å

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