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[[Image:2znl.png|left|200px]]


{{STRUCTURE_2znl|  PDB=2znl  |  SCENE=  }}
==Crystal structure of PA-PB1 complex form influenza virus RNA polymerase==
 
<StructureSection load='2znl' size='340' side='right'caption='[[2znl]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
===Crystal structure of PA-PB1 complex form influenza virus RNA polymerase===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2znl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/Puerto_Rico/8/1934(H1N1)) Influenza A virus (A/Puerto Rico/8/1934(H1N1))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZNL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZNL FirstGlance]. <br>
{{ABSTRACT_PUBMED_18660801}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2znl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2znl OCA], [https://pdbe.org/2znl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2znl RCSB], [https://www.ebi.ac.uk/pdbsum/2znl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2znl ProSAT]</span></td></tr>
==About this Structure==
</table>
[[2znl]] is a 2 chain structure of [[Polymerase acidic protein]] and [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZNL OCA].  
== Function ==
[https://www.uniprot.org/uniprot/PA_I34A1 PA_I34A1] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication.


==See Also==
==See Also==
*[[Polymerase acidic protein|Polymerase acidic protein]]
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
*[[RNA polymerase|RNA polymerase]]
__TOC__
 
</StructureSection>
==Reference==
[[Category: Large Structures]]
<ref group="xtra">PMID:018660801</ref><references group="xtra"/>
[[Category: Kawaguchi A]]
[[Category: Influenza a virus]]
[[Category: Kawai F]]
[[Category: RNA-directed RNA polymerase]]
[[Category: Nagata K]]
[[Category: Kawaguchi, A.]]
[[Category: Obayashi E]]
[[Category: Kawai, F.]]
[[Category: Park S-Y]]
[[Category: Nagata, K.]]
[[Category: Shibayama N]]
[[Category: Obayashi, E.]]
[[Category: Tame JRH]]
[[Category: Park, S Y.]]
[[Category: Yoshida H]]
[[Category: Shibayama, N.]]
[[Category: Tame, J R.H.]]
[[Category: Yoshida, H.]]
[[Category: Influenza a virus]]
[[Category: Nucleotide-binding]]
[[Category: Nucleotidyltransferase]]
[[Category: Pa]]
[[Category: Pb1]]
[[Category: Phosphoprotein]]
[[Category: Rna polymerase]]
[[Category: Rna replication]]
[[Category: Rna-directed rna polymerase]]
[[Category: Subunit interaction]]
[[Category: Transcription]]
[[Category: Transferase]]

Latest revision as of 13:58, 13 March 2024

Crystal structure of PA-PB1 complex form influenza virus RNA polymerase

2znl, resolution 2.30Å

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