3u2d: Difference between revisions
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==S. aureus GyrB ATPase domain in complex with small molecule inhibitor== | |||
<StructureSection load='3u2d' size='340' side='right'caption='[[3u2d]], [[Resolution|resolution]] 1.85Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3u2d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U2D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U2D FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=08B:4-BROMO-5-METHYL-N-[1-(3-NITROPYRIDIN-2-YL)PIPERIDIN-4-YL]-1H-PYRROLE-2-CARBOXAMIDE'>08B</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u2d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u2d OCA], [https://pdbe.org/3u2d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u2d RCSB], [https://www.ebi.ac.uk/pdbsum/3u2d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u2d ProSAT]</span></td></tr> | ||
[[3u2d]] is a 2 chain structure | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/GYRB_STAAU GYRB_STAAU] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings.[HAMAP-Rule:MF_01898] | |||
==See Also== | ==See Also== | ||
*[[Gyrase|Gyrase]] | *[[Gyrase 3D Structures|Gyrase 3D Structures]] | ||
__TOC__ | |||
</StructureSection> | |||
< | [[Category: Large Structures]] | ||
[[Category: Staphylococcus aureus]] | [[Category: Staphylococcus aureus]] | ||
[[Category: Boriack-Sjodin | [[Category: Boriack-Sjodin PA]] | ||
[[Category: Eakin | [[Category: Eakin AE]] | ||
[[Category: Prince | [[Category: Prince DB]] | ||
[[Category: Sherer | [[Category: Sherer BA]] | ||
Latest revision as of 10:16, 1 March 2024
S. aureus GyrB ATPase domain in complex with small molecule inhibitor
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