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[[Image:3qwi.png|left|200px]]


{{STRUCTURE_3qwi|  PDB=3qwi  |  SCENE=  }}
==Crystal structure of a 17beta-hydroxysteroid dehydrogenase (holo form) from fungus Cochliobolus lunatus in complex with NADPH and coumestrol==
 
<StructureSection load='3qwi' size='340' side='right'caption='[[3qwi]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
===Crystal structure of a 17beta-hydroxysteroid dehydrogenase (holo form) from fungus Cochliobolus lunatus in complex with NADPH and coumestrol===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3qwi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Curvularia_lunata Curvularia lunata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QWI FirstGlance]. <br>
{{ABSTRACT_PUBMED_21929506}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CUE:COUMESTROL'>CUE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qwi OCA], [https://pdbe.org/3qwi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qwi RCSB], [https://www.ebi.ac.uk/pdbsum/3qwi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qwi ProSAT]</span></td></tr>
[[3qwi]] is a 4 chain structure of [[Hydroxysteroid dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Cochliobolus_lunatus Cochliobolus lunatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWI OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/O93874_COCLU O93874_COCLU]


==See Also==
==See Also==
*[[Hydroxysteroid dehydrogenase|Hydroxysteroid dehydrogenase]]
*[[Hydroxysteroid dehydrogenase 3D structures|Hydroxysteroid dehydrogenase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:021929506</ref><references group="xtra"/>
[[Category: Curvularia lunata]]
[[Category: Cochliobolus lunatus]]
[[Category: Large Structures]]
[[Category: Estradiol 17-beta-dehydrogenase]]
[[Category: Brunskole M]]
[[Category: Brunskole, M.]]
[[Category: Cassetta A]]
[[Category: Cassetta, A.]]
[[Category: Krastanova I]]
[[Category: Krastanova, I.]]
[[Category: Kristan K]]
[[Category: Kristan, K.]]
[[Category: Lamba D]]
[[Category: Lamba, D.]]
[[Category: Lanisnik Rizner T]]
[[Category: Rizner, T Lanisnik.]]
[[Category: Stojan J]]
[[Category: Stojan, J.]]
[[Category: 17beta-hydroxysteroid dehydrogenase]]
[[Category: Cytosol]]
[[Category: Flavonoid]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
[[Category: Phytoestrogen]]
[[Category: Rossmann fold]]
[[Category: Short chain dehydrogenase/reductase]]

Latest revision as of 12:01, 14 March 2024

Crystal structure of a 17beta-hydroxysteroid dehydrogenase (holo form) from fungus Cochliobolus lunatus in complex with NADPH and coumestrol

3qwi, resolution 2.50Å

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