2a26: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "2a26" [edit=sysop:move=sysop] |
No edit summary |
||
| (7 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Crystal structure of the N-terminal, dimerization domain of Siah Interacting Protein== | |||
<StructureSection load='2a26' size='340' side='right'caption='[[2a26]], [[Resolution|resolution]] 1.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2a26]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A26 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A26 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CXS:3-CYCLOHEXYL-1-PROPYLSULFONIC+ACID'>CXS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a26 OCA], [https://pdbe.org/2a26 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a26 RCSB], [https://www.ebi.ac.uk/pdbsum/2a26 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a26 ProSAT]</span></td></tr> | ||
[[2a26]] is a 3 chain structure with sequence from [ | </table> | ||
== Function == | |||
== | [https://www.uniprot.org/uniprot/CYBP_HUMAN CYBP_HUMAN] May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).<ref>PMID:16085652</ref> | ||
< | == References == | ||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Ely | [[Category: Large Structures]] | ||
[[Category: Fukushima | [[Category: Ely KR]] | ||
[[Category: Leone | [[Category: Fukushima T]] | ||
[[Category: Li | [[Category: Leone M]] | ||
[[Category: Liddington | [[Category: Li C]] | ||
[[Category: Matsuzawa | [[Category: Liddington RC]] | ||
[[Category: Olson | [[Category: Matsuzawa S]] | ||
[[Category: Pellecchia | [[Category: Olson AJ]] | ||
[[Category: Preece | [[Category: Pellecchia M]] | ||
[[Category: Reed | [[Category: Preece NE]] | ||
[[Category: Santelli | [[Category: Reed JC]] | ||
[[Category: Santelli E]] | |||
Latest revision as of 09:10, 14 February 2024
Crystal structure of the N-terminal, dimerization domain of Siah Interacting Protein
| ||||||||||||
