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[[Image:4fbe.jpg|left|200px]]


{{STRUCTURE_4fbe| PDB=4fbe | SCENE= }}
==Crystal structure of the C136A/C164A variant of mitochondrial isoform of glutaminyl cyclase from Drosophila melanogaster==
<StructureSection load='4fbe' size='340' side='right'caption='[[4fbe]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4fbe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FBE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FBE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PBD:1-(3,4-DIMETHOXYPHENYL)-3-[3-(1H-IMIDAZOL-1-YL)PROPYL]THIOUREA'>PBD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fbe OCA], [https://pdbe.org/4fbe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fbe RCSB], [https://www.ebi.ac.uk/pdbsum/4fbe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fbe ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q86PD7_DROME Q86PD7_DROME]


===Crystal structure of the C136A/C164A variant of mitochondrial isoform of glutaminyl cyclase from Drosophila melanogaster===
==See Also==
 
*[[Glutaminyl cyclase|Glutaminyl cyclase]]
{{ABSTRACT_PUBMED_22897232}}
__TOC__
 
</StructureSection>
==About this Structure==
[[4fbe]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FBE OCA].
 
==Reference==
<ref group="xtra">PMID:022897232</ref><references group="xtra"/>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Koch, B.]]
[[Category: Large Structures]]
[[Category: Kolenko, P.]]
[[Category: Koch B]]
[[Category: Ruiz-Carilo, D.]]
[[Category: Kolenko P]]
[[Category: Stubbs, M T.]]
[[Category: Ruiz-Carilo D]]
[[Category: Alpha/beta hydrolase]]
[[Category: Stubbs MT]]
[[Category: Alzheimer's disease]]
[[Category: Hydrolase]]
[[Category: Pe]]
[[Category: Pglu formation]]
[[Category: Pglu-amyloid]]
[[Category: Pyroglutamate]]
[[Category: Transferase]]

Latest revision as of 15:20, 14 March 2024

Crystal structure of the C136A/C164A variant of mitochondrial isoform of glutaminyl cyclase from Drosophila melanogaster

4fbe, resolution 1.88Å

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