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[[Image:1f6t.png|left|200px]]


{{STRUCTURE_1f6t|  PDB=1f6t  |  SCENE=  }}
==STRUCTURE OF THE NUCLEOSIDE DIPHOSPHATE KINASE/ALPHA-BORANO(RP)-TDP.MG COMPLEX==
 
<StructureSection load='1f6t' size='340' side='right'caption='[[1f6t]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
===STRUCTURE OF THE NUCLEOSIDE DIPHOSPHATE KINASE/ALPHA-BORANO(RP)-TDP.MG COMPLEX===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1f6t]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F6T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F6T FirstGlance]. <br>
{{ABSTRACT_PUBMED_10899107}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TBD:2*-DEOXY-THYMIDINE-5*-ALPHA+BORANO+DIPHOSPHATE+(ISOMER+RP)'>TBD</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f6t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f6t OCA], [https://pdbe.org/1f6t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f6t RCSB], [https://www.ebi.ac.uk/pdbsum/1f6t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f6t ProSAT]</span></td></tr>
[[1f6t]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F6T OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/NDKC_DICDI NDKC_DICDI]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f6/1f6t_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f6t ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Nucleoside diphosphate kinase|Nucleoside diphosphate kinase]]
*[[Nucleoside diphosphate kinase 3D structures|Nucleoside diphosphate kinase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:010899107</ref><references group="xtra"/>
[[Category: Dictyostelium discoideum]]
[[Category: Dictyostelium discoideum]]
[[Category: Nucleoside-diphosphate kinase]]
[[Category: Large Structures]]
[[Category: Boretto, J.]]
[[Category: Boretto J]]
[[Category: Canard, B.]]
[[Category: Canard B]]
[[Category: Deville-Bonne, D.]]
[[Category: Deville-Bonne D]]
[[Category: Guerreiro, C.]]
[[Category: Guerreiro C]]
[[Category: Janin, J.]]
[[Category: Janin J]]
[[Category: Sarfati, S.]]
[[Category: Sarfati S]]
[[Category: Schneider, B.]]
[[Category: Schneider B]]
[[Category: Veron, M.]]
[[Category: Veron M]]
[[Category: Anti-hiv nucleoside analogue]]
[[Category: Boranophosphate]]
[[Category: Nucleoside diphosphate kinase]]
[[Category: Phosphorylation]]
[[Category: Transferase]]

Latest revision as of 07:11, 7 February 2024

STRUCTURE OF THE NUCLEOSIDE DIPHOSPHATE KINASE/ALPHA-BORANO(RP)-TDP.MG COMPLEX

1f6t, resolution 1.92Å

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